Sex Differences in Cardiometabolic Risk Factors among Hispanic/Latino Youth

Carmen R. Isasi*, Christina M. Parrinello, Guadalupe X. Ayala, Alan M. Delamater, Krista M. Perreira, Martha L. Daviglus, John P. Elder, Ashley N. Marchante, Shrikant I. Bangdiwala, Linda Van Horn, Mercedes R. Carnethon

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

48 Scopus citations


Objective To determine the prevalence of obesity and cardiometabolic risk in US Hispanic/Latino youth and examine whether there are disparities by sex in cardiometabolic risk factors. Study design Study of Latino Youth is a population-based cross-sectional study of 1466 Hispanic/Latino youth (8-16 years old) who were recruited from 4 urban US communities (Bronx, NY, Chicago, IL, Miami, FL, and San Diego, CA) in 2012-2014. The majority of children were US-born (78%) and from low-income and immigrant families. Cardiometabolic risk factors were defined by the use of national age- and sex-specific guidelines. Results The prevalence of obesity was 26.5%. The prevalence of class II-III obesity, diabetes, and dyslipidemia was high (9.7%, 16.5%, and 23.3%, respectively). The prevalence of cardiometabolic risk factors increased with severity of obesity in both boys and girls. Boys had a greater prevalence of diabetes and of elevated blood pressure than girls (20.9% vs 11.8% and 8.5% vs 3.3%). In multivariable analyses, younger boys were more likely to have obesity class II-III than girls (OR 3.59; 95% CI 1.44-8.97). Boys were more likely to have prediabetes than girls (OR 2.02; 95% CI 1.35-3.02), and the association was stronger at older ages. Conclusions The prevalence of cardiometabolic risk factors was high in this sample of Hispanic youth. Boys had a more adverse cardiometabolic profile compared with girls that may put them at higher risk of diabetes and cardiovascular disease later in life. Reasons for this disparity and the long-term clinical implications remain to be elucidated.

Original languageEnglish (US)
Pages (from-to)121-127.e1
Journaljournal of pediatrics
StatePublished - Sep 1 2016


  • CVD risk factors
  • Hispanic children
  • cardiometabolic risk factors
  • obesity
  • prediabetes

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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