Shaping the dynamic mitochondrial network

Laura L. Lackner

doi:10.1186/1741-7007-12-35

Shaping the dynamic mitochondrial network

Laura L. Lackner^*

^*Corresponding author for this work

Molecular Biosciences

Research output: Contribution to journal › Review article › peer-review

90 Scopus citations

Abstract

In a majority of cell types, mitochondria form highly dynamic, tubular networks. Maintaining the shape of this complex network is critical for both mitochondrial and cellular function and involves the activities of mitochondrial division, fusion, motility, and tethering. Recent studies have advanced our understanding of the molecular mechanisms underlying these conserved activities and their integration with cellular needs.

Original language	English (US)
Article number	35
Journal	BMC Biology
Volume	12
DOIs	https://doi.org/10.1186/1741-7007-12-35
State	Published - May 27 2014

ASJC Scopus subject areas

Agricultural and Biological Sciences(all)
Ecology, Evolution, Behavior and Systematics
Biochemistry, Genetics and Molecular Biology(all)
Structural Biology
Physiology
Biotechnology
Plant Science
Cell Biology
Developmental Biology

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10.1186/1741-7007-12-35

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title = "Shaping the dynamic mitochondrial network",

abstract = "In a majority of cell types, mitochondria form highly dynamic, tubular networks. Maintaining the shape of this complex network is critical for both mitochondrial and cellular function and involves the activities of mitochondrial division, fusion, motility, and tethering. Recent studies have advanced our understanding of the molecular mechanisms underlying these conserved activities and their integration with cellular needs.",

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AU - Lackner, Laura L.

PY - 2014/5/27

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N2 - In a majority of cell types, mitochondria form highly dynamic, tubular networks. Maintaining the shape of this complex network is critical for both mitochondrial and cellular function and involves the activities of mitochondrial division, fusion, motility, and tethering. Recent studies have advanced our understanding of the molecular mechanisms underlying these conserved activities and their integration with cellular needs.

AB - In a majority of cell types, mitochondria form highly dynamic, tubular networks. Maintaining the shape of this complex network is critical for both mitochondrial and cellular function and involves the activities of mitochondrial division, fusion, motility, and tethering. Recent studies have advanced our understanding of the molecular mechanisms underlying these conserved activities and their integration with cellular needs.

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DO - 10.1186/1741-7007-12-35

M3 - Review article

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SN - 1741-7007

VL - 12

JO - BMC Biology

JF - BMC Biology

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Shaping the dynamic mitochondrial network

Abstract

ASJC Scopus subject areas

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