Short-term resistance training with instability reduces impairment in V wave and H reflex in individuals with Parkinson's disease

Carla Silva-Batista, Jumes Leopoldino de Oliveira Lira, Fabian Jude David, Daniel Montie Corcos, Eugenia Casella Tavares Mattos, Daniel Boari Coelho, Andrea C. de Lima-Pardini, Camila Torriani-Pasin, Tatiana Beline de Freitas, Carlos Ugrinowitsch

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Abstract

This study had two objectives: 1) to compare the effects of 3 wk of resistance training (RT) and resistance training with instability (RTI) on evoked reflex responses at rest and during maximal voluntary isometric contraction (MVIC) of individuals with Parkinson's disease (PD) and 2) to determine the effectiveness of RT and RTI in moving values of evoked reflex responses of individuals with PD toward values of age-matched healthy control subjects (HCs) (z-score analysis). Ten individuals in the RT group and 10 in the RTI group performed resistance exercises twice a week for 3 wk, but only the RTI group included unstable devices. The HC group (n = 10) were assessed at pretest only. Evoked reflex responses at rest (H reflex and M wave) and during MVIC [supramaximal M-wave amplitude (Msup) and supramaximal V-wave amplitude (Vsup)] of the plantar flexors were assessed before and after the experimental protocol. From pretraining to posttraining, only RTI increased ratio of maximal H-reflex amplitude to maximal M-wave amplitude at rest (Hmax/Mmax), Msup, Vsup/Msup, and peak torque of the plantar flexors (P < 0.05). At posttraining, RTI was more effective than RT in increasing resting Hmax and Vsup and in moving these values to those observed in HCs (P < 0.05). We conclude that short-term RTI is more effective than short-term RT in modulating H-reflex excitability and in increasing efferent neural drive, approaching average values of HCs. Thus short-term RTI may cause positive changes at the spinal and supraspinal levels in individuals with PD. NEW & NOTEWORTHY Maximal H-reflex amplitude (Hmax) at rest and efferent neural drive [i.e., supramaximal V-wave amplitude (Vsup)] to skeletal muscles during maximal contraction are impaired in individuals with Parkinson's disease. Short-term resistance training with instability was more effective than short-term resistance training alone in increasing Hmax and Vsup of individuals with Parkinson's disease, reaching the average values of healthy control subjects.

Original languageEnglish (US)
Pages (from-to)89-97
Number of pages9
JournalJournal of applied physiology (Bethesda, Md. : 1985)
Volume127
Issue number1
DOIs
StatePublished - Jul 1 2019

Keywords

  • descending drive
  • motor dysfunction
  • muscle strength
  • reflex arc
  • unstable device

ASJC Scopus subject areas

  • Physiology
  • Physiology (medical)

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    Silva-Batista, C., Lira, J. L. D. O., David, F. J., Corcos, D. M., Mattos, E. C. T., Boari Coelho, D., de Lima-Pardini, A. C., Torriani-Pasin, C., de Freitas, T. B., & Ugrinowitsch, C. (2019). Short-term resistance training with instability reduces impairment in V wave and H reflex in individuals with Parkinson's disease. Journal of applied physiology (Bethesda, Md. : 1985), 127(1), 89-97. https://doi.org/10.1152/japplphysiol.00902.2018