Shushing down the epigenetic landscape towards stem cell differentiation

Justin K. Ichida; Evangelos Kiskinis; Kevin Eggan

doi:10.1242/dev.049130

Shushing down the epigenetic landscape towards stem cell differentiation

Justin K. Ichida, Evangelos Kiskinis, Kevin Eggan^*

^*Corresponding author for this work

Neurology

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

In February 2010, researchers interested in stem cell biology gathered in Keystone, Colorado, USA to discuss their findings on the origins and behaviors of pluripotent and multipotent stem cells, and their therapeutic potential. Here, we review the presentations at that meeting and the questions that emerged concerning how a stem cell 'decides' to self-renew or differentiate, what their distinct properties are and how this information can be used to develop novel therapies.

Original language	English (US)
Pages (from-to)	2455-2460
Number of pages	6
Journal	Development
Volume	137
Issue number	15
DOIs	https://doi.org/10.1242/dev.049130
State	Published - Aug 1 2010

Funding

Keywords

Differentiation
Induced pluripotent stem cells
Reprogramming

ASJC Scopus subject areas

Molecular Biology
Developmental Biology

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10.1242/dev.049130

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Shushing down the epigenetic landscape towards stem cell differentiation

Abstract

Funding

Keywords

ASJC Scopus subject areas

Access to Document

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