Shushing down the epigenetic landscape towards stem cell differentiation

Justin K. Ichida, Evangelos Kiskinis, Kevin Eggan*

*Corresponding author for this work

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

In February 2010, researchers interested in stem cell biology gathered in Keystone, Colorado, USA to discuss their findings on the origins and behaviors of pluripotent and multipotent stem cells, and their therapeutic potential. Here, we review the presentations at that meeting and the questions that emerged concerning how a stem cell 'decides' to self-renew or differentiate, what their distinct properties are and how this information can be used to develop novel therapies.

Original languageEnglish (US)
Pages (from-to)2455-2460
Number of pages6
JournalDevelopment
Volume137
Issue number15
DOIs
StatePublished - Aug 1 2010

Keywords

  • Differentiation
  • Induced pluripotent stem cells
  • Reprogramming

ASJC Scopus subject areas

  • Molecular Biology
  • Developmental Biology

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