Significance of elevated transplant renal artery velocities in the postoperative renal transplant patient

Eric Siskind; Pamela Lombardi; Mark Blum; Richard Tyrell; Manuel Villa; Michael Kuncewitch; Elizabeth M. Olsen; Asha Alex; Leandro Lumermann; Madhu C. Bhaskaran; Kenar D. Jhaveri; Mala Sachdeva; Kellie Calderon; Craig Greben; Daniel Putterman; Eric Gandras; Drew Caplin; Catherine D' Agostino; John Pellerito; Gene Coppa; Ernesto P. Molmenti

doi:10.1111/ctr.12075

Significance of elevated transplant renal artery velocities in the postoperative renal transplant patient

Eric Siskind^*, Pamela Lombardi, Mark Blum, Richard Tyrell, Manuel Villa, Michael Kuncewitch, Elizabeth M. Olsen, Asha Alex, Leandro Lumermann, Madhu C. Bhaskaran, Kenar D. Jhaveri, Mala Sachdeva, Kellie Calderon, Craig Greben, Daniel Putterman, Eric Gandras, Drew Caplin, Catherine D' Agostino, John Pellerito, Gene CoppaErnesto P. Molmenti

^*Corresponding author for this work

Radiology

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

Introduction: Non-invasive imaging studies can provide visualization of allograft perfusion in the postoperative evaluation of newly transplanted renal allografts. Aim: The purpose of our study was to evaluate the significance of elevated renal artery velocities in the immediate postoperative period. Methods: Peak systolic velocities (PSVs) were obtained in the transplanted renal artery of 128 patients immediately after transplantation. Repeat allograft Doppler ultrasonography was performed on patients with elevated values. Results: Of the 128 patients, 57 (44.5%) had severely elevated Doppler velocities >400 cm/s on the initial studies. Three patients within this category had persistently elevated values of >400 cm/s, warranting angiographic visualization of the renal vessels. Stent placement within the transplanted renal artery was required in two of these patients. There was normalization of the PSV in the remaining patients. Conclusions: Routine allograft Doppler ultrasonography in the immediate postoperative period allows for visualization of allograft perfusion. Elevated renal artery velocities in the immediate postoperative period do not necessarily represent stenosis requiring intervention. Failure of the PSV to normalize may require further intervention, and angiography continues to be the gold standard.

Original language	English (US)
Pages (from-to)	E157-E160
Journal	Clinical Transplantation
Volume	27
Issue number	2
DOIs	https://doi.org/10.1111/ctr.12075
State	Published - Mar 2013

Keywords

Doppler sonography
Post-transplant monitoring
Renal blood flow
Renal transplantation
Transplant renal artery stenosis
Ultrasound imaging

ASJC Scopus subject areas

Transplantation

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/ctr.12075

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Siskind, E., Lombardi, P., Blum, M., Tyrell, R., Villa, M., Kuncewitch, M., Olsen, E. M., Alex, A., Lumermann, L., Bhaskaran, M. C., Jhaveri, K. D., Sachdeva, M., Calderon, K., Greben, C., Putterman, D., Gandras, E., Caplin, D., D' Agostino, C., Pellerito, J., ... Molmenti, E. P. (2013). Significance of elevated transplant renal artery velocities in the postoperative renal transplant patient. Clinical Transplantation, 27(2), E157-E160. https://doi.org/10.1111/ctr.12075

@article{c08640d9799f45f7a72c3a2201188a7e,

title = "Significance of elevated transplant renal artery velocities in the postoperative renal transplant patient",

abstract = "Introduction: Non-invasive imaging studies can provide visualization of allograft perfusion in the postoperative evaluation of newly transplanted renal allografts. Aim: The purpose of our study was to evaluate the significance of elevated renal artery velocities in the immediate postoperative period. Methods: Peak systolic velocities (PSVs) were obtained in the transplanted renal artery of 128 patients immediately after transplantation. Repeat allograft Doppler ultrasonography was performed on patients with elevated values. Results: Of the 128 patients, 57 (44.5%) had severely elevated Doppler velocities >400 cm/s on the initial studies. Three patients within this category had persistently elevated values of >400 cm/s, warranting angiographic visualization of the renal vessels. Stent placement within the transplanted renal artery was required in two of these patients. There was normalization of the PSV in the remaining patients. Conclusions: Routine allograft Doppler ultrasonography in the immediate postoperative period allows for visualization of allograft perfusion. Elevated renal artery velocities in the immediate postoperative period do not necessarily represent stenosis requiring intervention. Failure of the PSV to normalize may require further intervention, and angiography continues to be the gold standard.",

keywords = "Doppler sonography, Post-transplant monitoring, Renal blood flow, Renal transplantation, Transplant renal artery stenosis, Ultrasound imaging",

author = "Eric Siskind and Pamela Lombardi and Mark Blum and Richard Tyrell and Manuel Villa and Michael Kuncewitch and Olsen, {Elizabeth M.} and Asha Alex and Leandro Lumermann and Bhaskaran, {Madhu C.} and Jhaveri, {Kenar D.} and Mala Sachdeva and Kellie Calderon and Craig Greben and Daniel Putterman and Eric Gandras and Drew Caplin and {D' Agostino}, Catherine and John Pellerito and Gene Coppa and Molmenti, {Ernesto P.}",

year = "2013",

month = mar,

doi = "10.1111/ctr.12075",

language = "English (US)",

volume = "27",

pages = "E157--E160",

journal = "Clinical Transplantation",

issn = "0902-0063",

publisher = "Wiley-Blackwell Publishing Ltd",

number = "2",

}

Siskind, E, Lombardi, P, Blum, M, Tyrell, R, Villa, M, Kuncewitch, M, Olsen, EM, Alex, A, Lumermann, L, Bhaskaran, MC, Jhaveri, KD, Sachdeva, M, Calderon, K, Greben, C, Putterman, D, Gandras, E, Caplin, D, D' Agostino, C, Pellerito, J, Coppa, G & Molmenti, EP 2013, 'Significance of elevated transplant renal artery velocities in the postoperative renal transplant patient', Clinical Transplantation, vol. 27, no. 2, pp. E157-E160. https://doi.org/10.1111/ctr.12075

TY - JOUR

T1 - Significance of elevated transplant renal artery velocities in the postoperative renal transplant patient

AU - Siskind, Eric

AU - Lombardi, Pamela

AU - Blum, Mark

AU - Tyrell, Richard

AU - Villa, Manuel

AU - Kuncewitch, Michael

AU - Olsen, Elizabeth M.

AU - Alex, Asha

AU - Lumermann, Leandro

AU - Bhaskaran, Madhu C.

AU - Jhaveri, Kenar D.

AU - Sachdeva, Mala

AU - Calderon, Kellie

AU - Greben, Craig

AU - Putterman, Daniel

AU - Gandras, Eric

AU - Caplin, Drew

AU - D' Agostino, Catherine

AU - Pellerito, John

AU - Coppa, Gene

AU - Molmenti, Ernesto P.

PY - 2013/3

Y1 - 2013/3

N2 - Introduction: Non-invasive imaging studies can provide visualization of allograft perfusion in the postoperative evaluation of newly transplanted renal allografts. Aim: The purpose of our study was to evaluate the significance of elevated renal artery velocities in the immediate postoperative period. Methods: Peak systolic velocities (PSVs) were obtained in the transplanted renal artery of 128 patients immediately after transplantation. Repeat allograft Doppler ultrasonography was performed on patients with elevated values. Results: Of the 128 patients, 57 (44.5%) had severely elevated Doppler velocities >400 cm/s on the initial studies. Three patients within this category had persistently elevated values of >400 cm/s, warranting angiographic visualization of the renal vessels. Stent placement within the transplanted renal artery was required in two of these patients. There was normalization of the PSV in the remaining patients. Conclusions: Routine allograft Doppler ultrasonography in the immediate postoperative period allows for visualization of allograft perfusion. Elevated renal artery velocities in the immediate postoperative period do not necessarily represent stenosis requiring intervention. Failure of the PSV to normalize may require further intervention, and angiography continues to be the gold standard.

AB - Introduction: Non-invasive imaging studies can provide visualization of allograft perfusion in the postoperative evaluation of newly transplanted renal allografts. Aim: The purpose of our study was to evaluate the significance of elevated renal artery velocities in the immediate postoperative period. Methods: Peak systolic velocities (PSVs) were obtained in the transplanted renal artery of 128 patients immediately after transplantation. Repeat allograft Doppler ultrasonography was performed on patients with elevated values. Results: Of the 128 patients, 57 (44.5%) had severely elevated Doppler velocities >400 cm/s on the initial studies. Three patients within this category had persistently elevated values of >400 cm/s, warranting angiographic visualization of the renal vessels. Stent placement within the transplanted renal artery was required in two of these patients. There was normalization of the PSV in the remaining patients. Conclusions: Routine allograft Doppler ultrasonography in the immediate postoperative period allows for visualization of allograft perfusion. Elevated renal artery velocities in the immediate postoperative period do not necessarily represent stenosis requiring intervention. Failure of the PSV to normalize may require further intervention, and angiography continues to be the gold standard.

KW - Doppler sonography

KW - Post-transplant monitoring

KW - Renal blood flow

KW - Renal transplantation

KW - Transplant renal artery stenosis

KW - Ultrasound imaging

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U2 - 10.1111/ctr.12075

DO - 10.1111/ctr.12075

M3 - Article

C2 - 23347219

AN - SCOPUS:84876079973

SN - 0902-0063

VL - 27

SP - E157-E160

JO - Clinical Transplantation

JF - Clinical Transplantation

IS - 2

ER -

Significance of elevated transplant renal artery velocities in the postoperative renal transplant patient

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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