Silver-based nanodisk codes

Matthew J. Banholzer, Kyle D. Osberg, Shuzhou Li, Bryan F. Mangelson, George C Schatz, Chad A Mirkin

Research output: Contribution to journalArticlepeer-review

47 Scopus citations


We report a novel method for synthesizing silver-based nanodisk code (NDC) structures using on-wire lithography, where we employ milder synthetic and etching conditions than those used to synthesize the analogous gold structures. The silver structures exhibit stronger surface-enhanced Raman scattering signals than their Au counterparts at 633 and 532 nm excitation and, therefore, lead to lower limits of detection when used in the context of DNA-based detection assays. Finally, use of two enhancing nanostructured materials in one disk code dramatically increases the information storage density for encoding. For example, a disk code consisting of 5 gold disk pairs has 13 unique combinations of enhancing patterns, while one with 5 disk pairs that can be either gold or silver has 98.

Original languageEnglish (US)
Pages (from-to)5446-5452
Number of pages7
JournalACS Nano
Issue number9
StatePublished - Sep 28 2010


  • SERS
  • biodetection
  • encoding
  • on-wire lithography
  • surface-enhanced Raman scattering
  • tagging

ASJC Scopus subject areas

  • General Materials Science
  • General Engineering
  • General Physics and Astronomy


Dive into the research topics of 'Silver-based nanodisk codes'. Together they form a unique fingerprint.

Cite this