Silver sulfadiazine induced Clostridium difficile toxic megacolon in a burn patient: A case report

Lawrence J. Jennings; Marella Hanumadass

doi:10.1016/S0305-4179(98)00099-0

Silver sulfadiazine induced Clostridium difficile toxic megacolon in a burn patient: A case report

Lawrence J. Jennings, Marella Hanumadass^*

^*Corresponding author for this work

Pathology

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

A 53 yr old diabetic male presented with a 34% total body surface area (TBSA) deep partial- and full-thickness burns. On post burn days 4 and 9, all of his burns were excised and grafted. Although he had only been treated with topical antibiotics, he developed Clostridium difficile colitis after his second surgery that progressed to Toxic Megacolon and perforation. The incidence and treatment of Toxic Megacolon secondary to C. difficile is reviewed. Early diagnosis and treatment with colonoscopic decompression may obviate the need for surgery.

Original language	English (US)
Pages (from-to)	676-679
Number of pages	4
Journal	Burns
Volume	24
Issue number	7
DOIs	https://doi.org/10.1016/S0305-4179(98)00099-0
State	Published - Nov 1 1998

Keywords

Burn
Clostridium difficile
Pseudomembranous colitis
Toxic megacolon

ASJC Scopus subject areas

Surgery
Emergency Medicine
Critical Care and Intensive Care Medicine

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10.1016/S0305-4179(98)00099-0

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title = "Silver sulfadiazine induced Clostridium difficile toxic megacolon in a burn patient: A case report",

abstract = "A 53 yr old diabetic male presented with a 34% total body surface area (TBSA) deep partial- and full-thickness burns. On post burn days 4 and 9, all of his burns were excised and grafted. Although he had only been treated with topical antibiotics, he developed Clostridium difficile colitis after his second surgery that progressed to Toxic Megacolon and perforation. The incidence and treatment of Toxic Megacolon secondary to C. difficile is reviewed. Early diagnosis and treatment with colonoscopic decompression may obviate the need for surgery.",

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AB - A 53 yr old diabetic male presented with a 34% total body surface area (TBSA) deep partial- and full-thickness burns. On post burn days 4 and 9, all of his burns were excised and grafted. Although he had only been treated with topical antibiotics, he developed Clostridium difficile colitis after his second surgery that progressed to Toxic Megacolon and perforation. The incidence and treatment of Toxic Megacolon secondary to C. difficile is reviewed. Early diagnosis and treatment with colonoscopic decompression may obviate the need for surgery.

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KW - Toxic megacolon

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