Single all-fiber-based nanosecond-pulsed supercontinuum source for multispectral photoacoustic microscopy and optical coherence tomography

Xiao Shu, Magalie Bondu, Biqin Dong, Adrian Podoleanu, Lasse Leick, Hao F. Zhang

Research output: Contribution to journalArticlepeer-review

31 Scopus citations

Abstract

We report the usefulness of a single all-fiber-based supercontinuum (SC) source for combined photoacoustic microscopy (PAM) and optical coherence tomography (OCT). The SC light is generated by a tapered photonic crystal fiber pumped by a nanosecond pulsed master oscillator power amplifier at 1064 nm. The spectrum is split into a shorter wavelength band (500-800 nm) for single/multispectral PAM and a longer wavelength band (800-900 nm) band for OCT. In vivo mouse ear imaging was achieved with an integrated dual-modality system. We further demonstrated its potential for spectroscopic photoacoustic imaging by doing multispectral measurements on retinal pigment epithelium and blood samples with 15-nm linewidth.

Original languageEnglish (US)
Pages (from-to)2743-2746
Number of pages4
JournalOptics Letters
Volume41
Issue number12
DOIs
StatePublished - Jun 15 2016

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

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