Single course versus maintenance bacillus Calmette-Guerin therapy for superficial bladder tumors: a prospective, randomized trial.

M. A. Hudson; T. L. Ratliff; D. P. Gillen; E. O. Haaff; S. M. Dresner; W. J. Catalona

doi:10.1016/S0022-5347(17)43125-9

Single course versus maintenance bacillus Calmette-Guerin therapy for superficial bladder tumors: a prospective, randomized trial.

M. A. Hudson^*, T. L. Ratliff, D. P. Gillen, E. O. Haaff, S. M. Dresner, W. J. Catalona

^*Corresponding author for this work

Urology

Research output: Contribution to journal › Article › peer-review

131 Scopus citations

Abstract

A total of 42 patients with recurrent superficial bladder tumors or carcinoma in situ entered a prospective, randomized trial to compare the efficacy of bacillus Calmette-Guerin therapy with and without quarterly maintenance instillations of bacillus Calmette-Guerin. Maintenance therapy did not reduce further bladder tumor recurrence rates or the interval to recurrence in patients who responded to the initial course of therapy. However, prolongation of toxicity was observed with maintenance bacillus Calmette-Guerin therapy.

Original language	English (US)
Pages (from-to)	295-298
Number of pages	4
Journal	The Journal of urology
Volume	138
Issue number	2
DOIs	https://doi.org/10.1016/S0022-5347(17)43125-9
State	Published - Aug 1987

ASJC Scopus subject areas

Urology

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title = "Single course versus maintenance bacillus Calmette-Guerin therapy for superficial bladder tumors: a prospective, randomized trial.",

abstract = "A total of 42 patients with recurrent superficial bladder tumors or carcinoma in situ entered a prospective, randomized trial to compare the efficacy of bacillus Calmette-Guerin therapy with and without quarterly maintenance instillations of bacillus Calmette-Guerin. Maintenance therapy did not reduce further bladder tumor recurrence rates or the interval to recurrence in patients who responded to the initial course of therapy. However, prolongation of toxicity was observed with maintenance bacillus Calmette-Guerin therapy.",

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AU - Gillen, D. P.

AU - Haaff, E. O.

AU - Dresner, S. M.

AU - Catalona, W. J.

PY - 1987/8

Y1 - 1987/8

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AB - A total of 42 patients with recurrent superficial bladder tumors or carcinoma in situ entered a prospective, randomized trial to compare the efficacy of bacillus Calmette-Guerin therapy with and without quarterly maintenance instillations of bacillus Calmette-Guerin. Maintenance therapy did not reduce further bladder tumor recurrence rates or the interval to recurrence in patients who responded to the initial course of therapy. However, prolongation of toxicity was observed with maintenance bacillus Calmette-Guerin therapy.

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Single course versus maintenance bacillus Calmette-Guerin therapy for superficial bladder tumors: a prospective, randomized trial.

Abstract

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