TY - JOUR
T1 - Single-Shot Coronary Quiescent-Interval Slice-Selective Magnetic Resonance Angiography Using Compressed Sensing
T2 - A Feasibility Study in Patients with Congenital Heart Disease
AU - Shen, Daming
AU - Edelman, Robert R.
AU - Robinson, Joshua D
AU - Haji-Valizadeh, Hassan
AU - Messina, Marci
AU - Giri, Shivraman
AU - Koktzoglou, Ioannis
AU - Rigsby, Cynthia K
AU - Kim, Daniel
N1 - Funding Information:
Key Words: compressed sensing (CS), congenital heart disease, coronary origins, MRA, MRI, quiescent-interval slice-selective (QISS) From the *Biomedical Engineering, Northwestern University, Evanston; †Department of Radiology, Northwestern University Feinberg School of Medicine, Chicago; ‡Department of Radiology, NorthShore University HealthSystem, Evanston; and §Division of Pediatric Cardiology and ||Department of Medical Imaging, Ann & Robert H. Lurie Children's Hospital of Chicago; ¶Cardiovascular MR R&D, Siemens Healthineers; and #Department of Radiology, University of Chicago Pritzker School of Medicine, Chicago, IL. Received for publication January 25, 2018; accepted April 7, 2018. Correspondence to: Daniel Kim, PhD, Department of Radiology, Northwestern University, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611 (e‐mail: daniel.kim3@northwestern.edu). This work was supported in part by funding from the National Institutes of Health (R01HL116895, R01HL115828, R01HL130093, R01HL138578, R21EB024315, R21AG055954). The authors declare no conflict of interest. Supplemental digital contents are available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal’s Web site (www.jcat.org). Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved. DOI: 10.1097/RCT.0000000000000760
Publisher Copyright:
© Wolters Kluwer Health, Inc. All rights reserved.
PY - 2018/9/1
Y1 - 2018/9/1
N2 - Objective The aim of this study was to determine whether it is feasible to visualize the coronary origins in patients with congenital heart disease (CHD) using single-shot coronary quiescent-interval slice-selective (QISS) magnetic resonance angiography (MRA) with compressed sensing (CS). Methods This retrospective study leveraged a parent study, which aimed to compare breath-hold, 2.1-fold accelerated, 2-shot coronary QISS MRA and clinical standard contrast-enhanced (CE) MRA in 14 patients with CHD (mean age, 17.0 ± 8.6 years, 6 females and 8 males). We evaluated the feasibility of single-shot coronary QISS MRA by retrospectively undersampling the 2-shot data set by an additional factor of 2, performing CS reconstruction, and comparing the retrospectively derived single-shot QISS MRA to 2-shot coronary QISS MRA and clinical standard CE MRA. For quantitative analysis, structural similarity index and normalized root mean square error were calculated. For qualitative analysis, 2 experienced readers scored the conspicuity of coronary origins on a 5-point Likert scale (1 = nondiagnostic, 2 = poor, 3 = clinically acceptable, 4 = good, 5 = excellent). Results Compared with 2-shot QISS, single-shot QISS produced normalized root mean square error of 5.8% ± 0.8% and structural similarity index of 95.4% ± 1.6%, suggesting high data fidelity by CS reconstruction. Compared with the mean conspicuity scores for clinical CE MRA (4.2 ± 0.5 and 4.1 ± 0.6 for right and left coronary origins, respectively), the mean conspicuity scores were not significantly different (P > 0.3) for 2-shot QISS (4.4 ± 0.9 and 4.2 ± 1.1, respectively) and single-shot QISS with CS (4.3 ± 1.1 and 3.8 ± 1.3, respectively) and deemed clinically acceptable to good (scores ≥3.0). Conclusions This study shows that it is feasible to visualize the coronary origins in patients with CHD with clinically acceptable to good image quality using single-shot coronary QISS MRA with CS.
AB - Objective The aim of this study was to determine whether it is feasible to visualize the coronary origins in patients with congenital heart disease (CHD) using single-shot coronary quiescent-interval slice-selective (QISS) magnetic resonance angiography (MRA) with compressed sensing (CS). Methods This retrospective study leveraged a parent study, which aimed to compare breath-hold, 2.1-fold accelerated, 2-shot coronary QISS MRA and clinical standard contrast-enhanced (CE) MRA in 14 patients with CHD (mean age, 17.0 ± 8.6 years, 6 females and 8 males). We evaluated the feasibility of single-shot coronary QISS MRA by retrospectively undersampling the 2-shot data set by an additional factor of 2, performing CS reconstruction, and comparing the retrospectively derived single-shot QISS MRA to 2-shot coronary QISS MRA and clinical standard CE MRA. For quantitative analysis, structural similarity index and normalized root mean square error were calculated. For qualitative analysis, 2 experienced readers scored the conspicuity of coronary origins on a 5-point Likert scale (1 = nondiagnostic, 2 = poor, 3 = clinically acceptable, 4 = good, 5 = excellent). Results Compared with 2-shot QISS, single-shot QISS produced normalized root mean square error of 5.8% ± 0.8% and structural similarity index of 95.4% ± 1.6%, suggesting high data fidelity by CS reconstruction. Compared with the mean conspicuity scores for clinical CE MRA (4.2 ± 0.5 and 4.1 ± 0.6 for right and left coronary origins, respectively), the mean conspicuity scores were not significantly different (P > 0.3) for 2-shot QISS (4.4 ± 0.9 and 4.2 ± 1.1, respectively) and single-shot QISS with CS (4.3 ± 1.1 and 3.8 ± 1.3, respectively) and deemed clinically acceptable to good (scores ≥3.0). Conclusions This study shows that it is feasible to visualize the coronary origins in patients with CHD with clinically acceptable to good image quality using single-shot coronary QISS MRA with CS.
KW - MRA
KW - MRI
KW - compressed sensing (CS)
KW - congenital heart disease
KW - coronary origins
KW - quiescent-interval slice-selective (QISS)
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U2 - 10.1097/RCT.0000000000000760
DO - 10.1097/RCT.0000000000000760
M3 - Article
C2 - 29958198
AN - SCOPUS:85053866506
VL - 42
SP - 739
EP - 746
JO - Journal of Computer Assisted Tomography
JF - Journal of Computer Assisted Tomography
SN - 0363-8715
IS - 5
ER -