Abstract
We report a case of a child with pre-B cell acute lymphoblastic leukemia undergoing maintenance chemotherapy with 6-mercaptopurine and methotrexate (MTX) who developed sinusoidal obstruction syndrome after being treated with ciprofloxacin for BK viremia. This case represents a rare complication of maintenance therapy with MTX and 6-mercaptopurine, and suggests a drug interaction between ciprofloxacin and MTX.
Original language | English (US) |
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Pages (from-to) | e454-e455 |
Journal | Journal of pediatric hematology/oncology |
Volume | 39 |
Issue number | 8 |
DOIs | |
State | Published - 2017 |
Keywords
- acute lymphoblastic leukemia
- drug interaction
- maintenance chemotherapy
- sinusoidal obstruction syndrome
- veno-occlusive disease
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Hematology
- Oncology