Six3 dosage mediates the pathogenesis of holoprosencephaly

Keyphrases

• Six3 100%
• Holoprosencephaly 100%
• Alobar 50%
• Semilobar 50%
• Shh Signaling Pathway 16%
• Lobar 16%
• Hypomorphic mutation 16%
• Cerebral Hemispheres 16%
• Diencephalon 16%
• Rostral 16%
• In Vitro Activation 16%
• Ventral Midline 16%
• Shh Expression 16%
• Neural Ectoderm 16%
• FOXG1 16%

Biochemistry, Genetics and Molecular Biology

• down Regulation 100%
• Signal Transduction 50%
• Allele 50%
• Neural Plate 50%

Neuroscience

• Holoprosencephaly 100%
• Cell Signaling 16%
• In Vivo 16%
• Diencephalon 16%
• Neural Plate 16%