Skeletal demineralization in Turner's syndrome

Richard M. Shore; Russell W. Chesney; Richard B. Mazess; Philip G. Rose; Gerald J. Bargman

doi:10.1007/BF02411296

Skeletal demineralization in Turner's syndrome

Richard M. Shore, Russell W. Chesney, Richard B. Mazess, Philip G. Rose, Gerald J. Bargman^*

^*Corresponding author for this work

Radiology

Research output: Contribution to journal › Article › peer-review

91 Scopus citations

Abstract

The bone mineral status of 17 girls with Turner's syndrome was evaluated by single photon absorptiometry. Bone mineral content (BMC) was 25.4% below that predicted by normalization for age, sex, height, weight, and bone width. Only 25% of this demineralization could be attributed to delayed skeletal maturation. Bones of girls who received estrogen replacement therapy were less demineralized than those of the others. The bone mineral deficit became less pronounced with advancing age. It could not be determined if the apparent effect of estrogens was related to age or if the apparent improvement with age was really due to an effect of estrogen treatment. For 8 subjects followed longitudinally there was no significant change in the BMC deficit.

Original language	English (US)
Pages (from-to)	519-522
Number of pages	4
Journal	Calcified Tissue International
Volume	34
Issue number	1
DOIs	https://doi.org/10.1007/BF02411296
State	Published - Dec 1 1982

Keywords

Bone
Osteoporosis
Ovarian dysgenesis
Turner's syndrome

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Orthopedics and Sports Medicine
Endocrinology

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10.1007/BF02411296

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title = "Skeletal demineralization in Turner's syndrome",

abstract = "The bone mineral status of 17 girls with Turner's syndrome was evaluated by single photon absorptiometry. Bone mineral content (BMC) was 25.4% below that predicted by normalization for age, sex, height, weight, and bone width. Only 25% of this demineralization could be attributed to delayed skeletal maturation. Bones of girls who received estrogen replacement therapy were less demineralized than those of the others. The bone mineral deficit became less pronounced with advancing age. It could not be determined if the apparent effect of estrogens was related to age or if the apparent improvement with age was really due to an effect of estrogen treatment. For 8 subjects followed longitudinally there was no significant change in the BMC deficit.",

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AU - Shore, Richard M.

AU - Chesney, Russell W.

AU - Mazess, Richard B.

AU - Rose, Philip G.

AU - Bargman, Gerald J.

PY - 1982/12/1

Y1 - 1982/12/1

N2 - The bone mineral status of 17 girls with Turner's syndrome was evaluated by single photon absorptiometry. Bone mineral content (BMC) was 25.4% below that predicted by normalization for age, sex, height, weight, and bone width. Only 25% of this demineralization could be attributed to delayed skeletal maturation. Bones of girls who received estrogen replacement therapy were less demineralized than those of the others. The bone mineral deficit became less pronounced with advancing age. It could not be determined if the apparent effect of estrogens was related to age or if the apparent improvement with age was really due to an effect of estrogen treatment. For 8 subjects followed longitudinally there was no significant change in the BMC deficit.

AB - The bone mineral status of 17 girls with Turner's syndrome was evaluated by single photon absorptiometry. Bone mineral content (BMC) was 25.4% below that predicted by normalization for age, sex, height, weight, and bone width. Only 25% of this demineralization could be attributed to delayed skeletal maturation. Bones of girls who received estrogen replacement therapy were less demineralized than those of the others. The bone mineral deficit became less pronounced with advancing age. It could not be determined if the apparent effect of estrogens was related to age or if the apparent improvement with age was really due to an effect of estrogen treatment. For 8 subjects followed longitudinally there was no significant change in the BMC deficit.

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Skeletal demineralization in Turner's syndrome

Abstract

Keywords

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