@article{e2b8a2ae226d4b02807a81091e04157f,
title = "Skin-interfaced microfluidic system with personalized sweating rate and sweat chloride analytics for sports science applications",
abstract = "Advanced capabilities in noninvasive, in situ monitoring of sweating rate and sweat electrolyte losses could enable real-time personalized fluid-electrolyte intake recommendations. Established sweat analysis techniques using absorbent patches require post-collection harvesting and benchtop analysis of sweat and are thus impractical for ambulatory use. Here, we introduce a skin-interfaced wearable microfluidic device and smartphone image processing platform that enable analysis of regional sweating rate and sweat chloride concentration ([Cl−]). Systematic studies (n = 312 athletes) establish significant correlations for regional sweating rate and sweat [Cl−] in a controlled environment and during competitive sports under varying environmental conditions. The regional sweating rate and sweat [Cl−] results serve as inputs to algorithms implemented on a smartphone software application that predicts whole-body sweating rate and sweat [Cl−]. This low-cost wearable sensing approach could improve the accessibility of physiological insights available to sports scientists, practitioners, and athletes to inform hydration strategies in real-world ambulatory settings.",
author = "Baker, {Lindsay B.} and Model, {Jeffrey B.} and Barnes, {Kelly A.} and Anderson, {Melissa L.} and Lee, {Stephen P.} and Lee, {Khalil A.} and Brown, {Shyretha D.} and Reimel, {Adam J.} and Roberts, {Timothy J.} and Nuccio, {Ryan P.} and Bonsignore, {Justina L.} and Ungaro, {Corey T.} and Carter, {James M.} and Weihua Li and Seib, {Melissa S.} and Reeder, {Jonathan T.} and Aranyosi, {Alexander J.} and Rogers, {John A.} and Roozbeh Ghaffari",
note = "Funding Information: We thank the following for assistance with data collection: R. Reale, K. Dalrymple, M. King, K. Luhrs, and B. Sopena. We thank P. De Chavez and S. Qu for statistical analysis support and J. Stofan for support with study conceptualization and supervision. We also thank S. Chen for benchtop testing of sweat microfluidic patches. Funding: This study was funded by the Gatorade Sports Science Institute, a division of PepsiCo Inc. The views expressed in this manuscript are those of the authors and do not necessarily reflect the position or policy of PepsiCo Inc. We also acknowledge funding support provided by the Querrey Simpson Institute for Bioelectronics at Northwestern University. Publisher Copyright: Copyright {\textcopyright} 2020 The Authors,",
year = "2020",
month = dec,
day = "11",
doi = "10.1126/sciadv.abe3929",
language = "English (US)",
volume = "6",
journal = "Science advances",
issn = "2375-2548",
publisher = "American Association for the Advancement of Science",
number = "50",
}