Skull Base Chondrosarcoma. Evidence-Based Treatment Paradigms.

Orin Bloch, Andrew T. Parsa*

*Corresponding author for this work

Research output: Contribution to journalReview article

35 Scopus citations

Abstract

Chondrosarcomas are indolent but invasive chondroid malignancies that can form in the skull base. Standard management of chondrosarcoma involves surgical resection and adjuvant radiation therapy. This review evaluates evidence from the literature to assess the importance of the surgical approach and extent of resection on outcomes for patients with skull base chondrosarcoma. Also evaluated is the ability of the multiple modalities of radiation therapy, such as conventional fractionated radiotherapy, proton beam, and stereotactic radiosurgery, to control tumor growth. Finally, emerging therapies for the treatment of skull-base chondrosarcoma are discussed.

Original languageEnglish (US)
Pages (from-to)89-96
Number of pages8
JournalNeurosurgery Clinics of North America
Volume24
Issue number1
DOIs
StatePublished - Jan 1 2013

Keywords

  • Chondrosarcoma
  • Microsurgery
  • Radiotherapy
  • Skull base

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

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