Sleep Disorders in Atypical Parkinsonism

Sabra M. Abbott*, Aleksandar Videnovic

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

27 Scopus citations


Sleep disorders are commonly observed in atypical parkinsonism, with particular disorders occurring more frequently in specific parkinsonian disorders. Multiple system atrophy (MSA) is a synucleinopathy often associated with nocturnal stridor, which is a serious, but treatable, condition highly specific to MSA. In addition, this disorder is strongly associated with rapid eye movement sleep behavior disorder (RBD), which is also observed in dementia with Lewy bodies. RBD is far less prevalent in progressive supranuclear palsy (PSP), which is a tauopathy. Insomnia and impaired sleep architecture are the most common sleep abnormalities observed in PSP. Corticobasilar degeneration is also a tauopathy, but has far fewer sleep complaints associated with it than PSP. In this article, we review the spectrum of sleep dysfunction across the atypical parkinsonian disorders, emphasize the importance of evaluating for sleep disorders in patients with parkinsonian symptoms, and point to sleep characteristics that can provide diagnostic clues to the underlying parkinsonian disorder.

Original languageEnglish (US)
Pages (from-to)89-96
Number of pages8
JournalMovement Disorders Clinical Practice
Issue number2
StatePublished - Jun 2014


  • REM sleep behavior disorder
  • corticobasal degeneration
  • dementia with lewy bodies
  • insomnia
  • multiple system atrophy
  • progressive supranuclear palsy
  • sleep disorders

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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