Small Molecules, Big Effects: Tuning Adsorption and Catalytic Properties of Metal-Organic Frameworks

Xinyao Liu, Kent O. Kirlikovali, Zhijie Chen, Kaikai Ma, Karam B. Idrees, Ran Cao, Xuan Zhang, Timur Islamoglu, Yunling Liu, Omar K. Farha*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Metal-organic frameworks (MOFs) have emerged as a highly tunable class of porous materials, and in particular, zirconium-based MOFs (Zr-MOFs) have demonstrated the potential to address challenges in a variety of practical applications due to their excellent chemical and thermal stabilities. However, Zr-MOFs are typically synthesized using flammable and toxic organic solvents. An effective, green, scalable route to obtain high-quality Zr-MOFs has yet to be developed as these procedures typically yield Zr-MOFs with relatively lower crystallinities and porosities than those obtained via the former route. Herein, we report the aqueous synthesis of MOF-808, a versatile Zr-MOF, that yields products with high crystallinities and porosities that are comparable to those of solvothermally synthesized MOF-808. We demonstrate that modifying the carboxylic acid-based modulator used in this hydrothermal procedure enables the straightforward tuning of the pore environment in MOF-808. This approach can be leveraged to tune both the water adsorption properties of MOF-808 and the solid-state catalytic performance of MOF-808 toward the hydrolysis of a nerve agent simulant. We anticipate that the insight gained here extends beyond MOF-808 and that it will lead to similar advancements for other Zr-MOFs.

Original languageEnglish (US)
Pages (from-to)1444-1454
Number of pages11
JournalChemistry of Materials
Issue number4
StatePublished - Feb 23 2021

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)
  • Materials Chemistry

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