SnapShot: RNA Structure Probing Technologies

Paul D. Carlson, Molly E. Evans, Angela M. Yu, Eric J. Strobel, Julius B. Lucks

Research output: Contribution to journalShort surveypeer-review

5 Scopus citations

Abstract

Chemical probing coupled to high-throughput sequencing offers a flexible approach to uncover many aspects of RNA structure relevant to its cellular function. With a wide variety of chemical probes available that each report on different features of RNA molecules, a broad toolkit exists for investigating in vivo and in vitro RNA structure and interactions with other molecules. Chemical probing coupled to high-throughput sequencing offers a flexible approach to uncover many aspects of RNA structure relevant to its cellular function. With a wide variety of chemical probes available that each report on different features of RNA molecules, a broad toolkit exists for investigating in vivo and in vitro RNA structure and interactions with other molecules.

Original languageEnglish (US)
Pages (from-to)600-600.e1
JournalCell
Volume175
Issue number2
DOIs
StatePublished - Oct 4 2018

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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