Socioeconomic status and the likelihood of antibiotic treatment for signs and symptoms of pulmonary exacerbation in children with cystic fibrosis

Michael S. Schechter*, Susanna A. McColley, Warren Regelmann, Stefanie J. Millar, David J. Pasta, Jeffrey S. Wagener, Michael W. Konstan, Wayne J. Morgan

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

24 Scopus citations

Abstract

Objective: To determine whether socioeconomic status (SES) influences the likelihood of antibiotic treatment of pulmonary exacerbations in patients with cystic fibrosis (CF). Study design: We used data on 9895 patients ≤18 years old from the Epidemiologic Study of CF. After establishing an individual baseline of clinical signs and symptoms, we ascertained whether antibiotics were prescribed when new signs/symptoms suggested a pulmonary exacerbation, adjusting for sex, presence of Pseudomonas aeruginosa, the number of new signs/symptoms, and baseline disease severity. Results: In a 12-month period, 20.0% of patients <6 years of age, 33.8% of patients 6 to 12 years of age, and 41.4% of patients 13 to 18 years of age were treated with any (oral, intravenous (IV), or inhaled) antibiotics; the percentage receiving IV antibiotics was 7.3%, 15.2%, and 20.9%, respectively. SES had little effect on treatment for pulmonary exacerbation with any antibiotics, but IV antibiotics were prescribed more frequently for patients with lower SES. Conclusions: SES-related disparities in CF health outcomes do not appear to be explained by differential treatment of pulmonary exacerbations.

Original languageEnglish (US)
Pages (from-to)819-824.e1
JournalJournal of Pediatrics
Volume159
Issue number5
DOIs
StatePublished - Nov 2011

Keywords

  • CF
  • Cystic fibrosis
  • ESCF
  • Epidemiologic Study of Cystic Fibrosis
  • Forced expiratory volume in 1 second
  • IV
  • Intravenous
  • MA
  • MEA
  • MIZ
  • Maternal educational attainment
  • Median household income by zip code
  • Medicaid or state insurance
  • SES
  • Socioeconomic status

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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