Soft microfluidic assemblies of sensors, circuits, and radios for the skin

Sheng Xu, Yihui Zhang, Lin Jia, Kyle E. Mathewson, Kyung In Jang, Jeonghyun Kim, Haoran Fu, Xian Huang, Pranav Chava, Renhan Wang, Sanat Bhole, Lizhe Wang, Yoon Joo Na, Yue Guan, Matthew Flavin, Zheshen Han, Yonggang Huang*, John A. Rogers

*Corresponding author for this work

Research output: Contribution to journalArticle

507 Citations (Scopus)

Abstract

When mounted on the skin, modern sensors, circuits, radios, and power supply systems have the potential to provide clinical-quality health monitoring capabilities for continuous use, beyond the confines of traditional hospital or laboratory facilities. The most well-developed component technologies are, however, broadly available only in hard, planar formats. As a result, existing options in system design are unable to effectively accommodate integration with the soft, textured, curvilinear, and time-dynamic surfaces of the skin. Here, we describe experimental and theoretical approaches for using ideas in soft microfluidics, structured adhesive surfaces, and controlled mechanical buckling to achieve ultralow modulus, highly stretchable systems that incorporate assemblies of high-modulus, rigid, state-of-the-art functional elements. The outcome is a thin, conformable device technology that can softly laminate onto the surface of the skin to enable advanced, multifunctional operation for physiological monitoring in a wireless mode.

Original languageEnglish (US)
Pages (from-to)70-74
Number of pages5
JournalScience
Volume344
Issue number6179
DOIs
StatePublished - Jan 1 2014

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Microfluidics
Radio
Skin
Technology
Electric Power Supplies
Hospital Laboratories
Physiologic Monitoring
Adhesives
Equipment and Supplies
Health

ASJC Scopus subject areas

  • General

Cite this

Xu, S., Zhang, Y., Jia, L., Mathewson, K. E., Jang, K. I., Kim, J., ... Rogers, J. A. (2014). Soft microfluidic assemblies of sensors, circuits, and radios for the skin. Science, 344(6179), 70-74. https://doi.org/10.1126/science.1250169
Xu, Sheng ; Zhang, Yihui ; Jia, Lin ; Mathewson, Kyle E. ; Jang, Kyung In ; Kim, Jeonghyun ; Fu, Haoran ; Huang, Xian ; Chava, Pranav ; Wang, Renhan ; Bhole, Sanat ; Wang, Lizhe ; Na, Yoon Joo ; Guan, Yue ; Flavin, Matthew ; Han, Zheshen ; Huang, Yonggang ; Rogers, John A. / Soft microfluidic assemblies of sensors, circuits, and radios for the skin. In: Science. 2014 ; Vol. 344, No. 6179. pp. 70-74.
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abstract = "When mounted on the skin, modern sensors, circuits, radios, and power supply systems have the potential to provide clinical-quality health monitoring capabilities for continuous use, beyond the confines of traditional hospital or laboratory facilities. The most well-developed component technologies are, however, broadly available only in hard, planar formats. As a result, existing options in system design are unable to effectively accommodate integration with the soft, textured, curvilinear, and time-dynamic surfaces of the skin. Here, we describe experimental and theoretical approaches for using ideas in soft microfluidics, structured adhesive surfaces, and controlled mechanical buckling to achieve ultralow modulus, highly stretchable systems that incorporate assemblies of high-modulus, rigid, state-of-the-art functional elements. The outcome is a thin, conformable device technology that can softly laminate onto the surface of the skin to enable advanced, multifunctional operation for physiological monitoring in a wireless mode.",
author = "Sheng Xu and Yihui Zhang and Lin Jia and Mathewson, {Kyle E.} and Jang, {Kyung In} and Jeonghyun Kim and Haoran Fu and Xian Huang and Pranav Chava and Renhan Wang and Sanat Bhole and Lizhe Wang and Na, {Yoon Joo} and Yue Guan and Matthew Flavin and Zheshen Han and Yonggang Huang and Rogers, {John A.}",
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Xu, S, Zhang, Y, Jia, L, Mathewson, KE, Jang, KI, Kim, J, Fu, H, Huang, X, Chava, P, Wang, R, Bhole, S, Wang, L, Na, YJ, Guan, Y, Flavin, M, Han, Z, Huang, Y & Rogers, JA 2014, 'Soft microfluidic assemblies of sensors, circuits, and radios for the skin', Science, vol. 344, no. 6179, pp. 70-74. https://doi.org/10.1126/science.1250169

Soft microfluidic assemblies of sensors, circuits, and radios for the skin. / Xu, Sheng; Zhang, Yihui; Jia, Lin; Mathewson, Kyle E.; Jang, Kyung In; Kim, Jeonghyun; Fu, Haoran; Huang, Xian; Chava, Pranav; Wang, Renhan; Bhole, Sanat; Wang, Lizhe; Na, Yoon Joo; Guan, Yue; Flavin, Matthew; Han, Zheshen; Huang, Yonggang; Rogers, John A.

In: Science, Vol. 344, No. 6179, 01.01.2014, p. 70-74.

Research output: Contribution to journalArticle

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AU - Xu, Sheng

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AU - Mathewson, Kyle E.

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AU - Kim, Jeonghyun

AU - Fu, Haoran

AU - Huang, Xian

AU - Chava, Pranav

AU - Wang, Renhan

AU - Bhole, Sanat

AU - Wang, Lizhe

AU - Na, Yoon Joo

AU - Guan, Yue

AU - Flavin, Matthew

AU - Han, Zheshen

AU - Huang, Yonggang

AU - Rogers, John A.

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Xu S, Zhang Y, Jia L, Mathewson KE, Jang KI, Kim J et al. Soft microfluidic assemblies of sensors, circuits, and radios for the skin. Science. 2014 Jan 1;344(6179):70-74. https://doi.org/10.1126/science.1250169