Soft-Tissue Infections of Ampicillin-Resistant Haemophilus influenzae Type b: The Use of Ampicillin and Nafcillin in Their Treatment

Ram Yogev*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

The combination of intravenous ampicillin sodium and nafcillin sodium followed by oral ampicillin and dicloxacillin sodium was effective in treating five infants with soft-tissue infections and bacteremia due to β-lactamase—producing, ampicillin-resistant Haemophilus influenzae type b. This antibiotic combination seems to be an effective alternative to chloramphenicol for treatment of nonmeningitic invasive disease due to moderately ampicillin-resistantH influenzae type b. The use of this combination should be in conjunction with appropriate in vitro tests whose results demonstrate synergism.

Original languageEnglish (US)
Pages (from-to)410-412
Number of pages3
JournalAmerican Journal of Diseases of Children
Volume135
Issue number5
DOIs
StatePublished - May 1981

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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