Soft tissue sarcoma: Clinical practice guidelines in oncology

George D. Demetri*, Laurence H. Baker, Derrick Beech, Robert Benjamin, Ephraim S. Casper, Ernest U. Conrad, Thomas F. DeLaney, David S. Ettinger, Martin J. Heslin, Ray J. Hutchinson, Krystyna Kiel, William G. Kraybill, G. Douglas Letson, James Neff, Richard J. O'Donnell, I. Benjamin Paz, Raphael E. Pollock, R. Lor Randall, Karen D. Schupak, Douglas S. TylerMargaret Von Mehren, Jeffrey Wayne

*Corresponding author for this work

Research output: Contribution to journalReview article

22 Scopus citations

Abstract

Sarcomas constitute a complex and diverse family of rare, clinicopathologically distinct malignant neoplasms of mesenchymal cell origin. The annual incidence of soft tissue sarcomas in the United States for 2004 is estimated to be about 8,680 cases, with an overall mortality rate of approximately 3,660 cases per year, including adults and children. The expertise of the NCCN institutions allows the panel to use their extensive experience in defining these consensus practice guidelines for the management of patients with sarcomas. These guidelines address sarcoma management from the perspective of four disease subtypes: soft tissue extremity sarcomas, retroperitoneal (including nongastrointestinal visceral) sarcomas, gastrointestinal stromal tumors and other intra-abdominal sarcomas, and the unique mesenchymal neoplasm known as desmoid tumor (or desmoid aggressive fibromatosis).

Original languageEnglish (US)
Pages (from-to)158-194
Number of pages37
JournalJNCCN Journal of the National Comprehensive Cancer Network
Volume3
Issue number2
StatePublished - Mar 1 2005

Keywords

  • Chemotherapy
  • Desmoid tumor
  • Gastrointestinal stromal tumors
  • NCCN Clinical Practice Guidelines
  • Radiation therapy
  • Retroperitoneal sarcomas
  • Soft tissue extremity sarcoma
  • Soft tissue sarcoma
  • Surgery

ASJC Scopus subject areas

  • Oncology

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    Demetri, G. D., Baker, L. H., Beech, D., Benjamin, R., Casper, E. S., Conrad, E. U., DeLaney, T. F., Ettinger, D. S., Heslin, M. J., Hutchinson, R. J., Kiel, K., Kraybill, W. G., Letson, G. D., Neff, J., O'Donnell, R. J., Paz, I. B., Pollock, R. E., Randall, R. L., Schupak, K. D., ... Wayne, J. (2005). Soft tissue sarcoma: Clinical practice guidelines in oncology. JNCCN Journal of the National Comprehensive Cancer Network, 3(2), 158-194.