Soft Wearable Systems for Colorimetric and Electrochemical Analysis of Biofluids

Roozbeh Ghaffari; Jungil Choi; Milan S. Raj; Shulin Chen; Stephen P. Lee; Jonathan T. Reeder; Alexander J. Aranyosi; Adam Leech; Weihua Li; Stephanie Schon; Jeffrey B. Model; John A. Rogers

doi:10.1002/adfm.201907269

Soft Wearable Systems for Colorimetric and Electrochemical Analysis of Biofluids

Roozbeh Ghaffari^*, Jungil Choi, Milan S. Raj, Shulin Chen, Stephen P. Lee, Jonathan T. Reeder, Alexander J. Aranyosi, Adam Leech, Weihua Li, Stephanie Schon, Jeffrey B. Model, John A. Rogers

^*Corresponding author for this work

Research output: Contribution to journal › Review article

3 Scopus citations

Abstract

Wearable monitoring systems provide valuable insights about the state of wellness, performance, and progression of diseases. Although conventional wearable systems have been effective in measuring a few key biophysical markers, they offer limited insights into biochemical activity and are otherwise cumbersome in ambulatory modes of use, relying on wired connections, mechanical straps, and bulky electronics. Recent advances in skin-interfaced microfluidics, stretchable/flexible electronics, and mechanics have created new wearable systems with capabilities in real-time, noninvasive analysis of sweat biochemistry in combination with biophysical metrics. Here, the latest technologies in multifunctional sweat sensing systems are presented with a focus on novel microfluidic designs, fully-integrated wireless electrochemical sensors, and hybrid biochemical/biophysical sensing capabilities, creating real-time physiological insights.

Original language	English (US)
Article number	1907269
Journal	Advanced Functional Materials
DOIs	https://doi.org/10.1002/adfm.201907269
State	Accepted/In press - Jan 1 2019

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Keywords

bioassays
bioelectronics
electrochemistry
microfluidics
personalized medicine

ASJC Scopus subject areas

Chemistry(all)
Materials Science(all)
Condensed Matter Physics

Cite this

Ghaffari, R., Choi, J., Raj, M. S., Chen, S., Lee, S. P., Reeder, J. T., Aranyosi, A. J., Leech, A., Li, W., Schon, S., Model, J. B., & Rogers, J. A. (Accepted/In press). Soft Wearable Systems for Colorimetric and Electrochemical Analysis of Biofluids. Advanced Functional Materials, [1907269]. https://doi.org/10.1002/adfm.201907269

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abstract = "Wearable monitoring systems provide valuable insights about the state of wellness, performance, and progression of diseases. Although conventional wearable systems have been effective in measuring a few key biophysical markers, they offer limited insights into biochemical activity and are otherwise cumbersome in ambulatory modes of use, relying on wired connections, mechanical straps, and bulky electronics. Recent advances in skin-interfaced microfluidics, stretchable/flexible electronics, and mechanics have created new wearable systems with capabilities in real-time, noninvasive analysis of sweat biochemistry in combination with biophysical metrics. Here, the latest technologies in multifunctional sweat sensing systems are presented with a focus on novel microfluidic designs, fully-integrated wireless electrochemical sensors, and hybrid biochemical/biophysical sensing capabilities, creating real-time physiological insights.",

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Soft Wearable Systems for Colorimetric and Electrochemical Analysis of Biofluids. / Ghaffari, Roozbeh; Choi, Jungil; Raj, Milan S.; Chen, Shulin; Lee, Stephen P.; Reeder, Jonathan T.; Aranyosi, Alexander J.; Leech, Adam; Li, Weihua; Schon, Stephanie; Model, Jeffrey B.; Rogers, John A.

In: Advanced Functional Materials, 01.01.2019.

Research output: Contribution to journal › Review article

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AU - Ghaffari, Roozbeh

AU - Choi, Jungil

AU - Raj, Milan S.

AU - Chen, Shulin

AU - Lee, Stephen P.

AU - Reeder, Jonathan T.

AU - Aranyosi, Alexander J.

AU - Leech, Adam

AU - Li, Weihua

AU - Schon, Stephanie

AU - Model, Jeffrey B.

AU - Rogers, John A.

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AB - Wearable monitoring systems provide valuable insights about the state of wellness, performance, and progression of diseases. Although conventional wearable systems have been effective in measuring a few key biophysical markers, they offer limited insights into biochemical activity and are otherwise cumbersome in ambulatory modes of use, relying on wired connections, mechanical straps, and bulky electronics. Recent advances in skin-interfaced microfluidics, stretchable/flexible electronics, and mechanics have created new wearable systems with capabilities in real-time, noninvasive analysis of sweat biochemistry in combination with biophysical metrics. Here, the latest technologies in multifunctional sweat sensing systems are presented with a focus on novel microfluidic designs, fully-integrated wireless electrochemical sensors, and hybrid biochemical/biophysical sensing capabilities, creating real-time physiological insights.

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KW - bioelectronics

KW - electrochemistry

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Access to Document

10.1002/adfm.201907269