Sonographic recognition of agenesis of the corpus callosum

Agenesis of the corpus callosum may be diagnosed successfully in vivo when sonograms demonstrate absence of corpus callosum; absence of pericallosal and cingulate sulci; 'sunburst' pattern of sulci along the medial surface of the hemisphere; wide interhemispheric fissure; elevation of the third ventricle; small, laterally positioned frontal horns with concave medial borders; large, laterally positioned and inverted cingulate gyri; and Probst lateral callosal bundles. Comparison of necropsy specimens with sonograms from eight patients with callosal agenesis illustrates the anatomic basis for these diagnostic features.