Sonographically monitored ovarian stimulation for assisted reproduction: A prospective, blind study

Edmond Confino*, Zvi Binor, Mary Wood Molo, Richard Rawlins, R. N. René Balos, R. N. Kimberly Mullaney, Ewa Radwanska

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


OBJECTIVE: To assess prospectively the appropriateness of follicular sonography alone for monitoring ovarian stimulation and to compare it to ovarian monitoring with both follicular sonography and hormone level determinations. STUDY DESIGN: Prospective, blind, clinical study in which the investigator made cycle management decisions based on follicular sonography only. RESULTS: Follicular sonography alone predicted 88% of the decisions made by the combination of follicular sonography, luteinizing hormone (LH), estradiol (E 2) and progesterone measurements. Follicular sonography was unable to predict abnormal E 2 patterns in eight (8%) of the patients' scans. Follicular sonography did not detect three (3%) patients with a premature LH surge. CONCLUSION: Follicular sonograms alone performed during ovarian stimulation predicted 88% of cycle decisions. One could argue that hormone measurements could be either reduced or eliminated during ovarian stimulation for assisted reproductive technology and that follicular sonography only would be a cost-effective compromise. The effect of such simplified monitoring on pregnancy rates would require further prospective evaluation.

Original languageEnglish (US)
Pages (from-to)7-10
Number of pages4
JournalJournal of Reproductive Medicine for the Obstetrician and Gynecologist
Issue number1
StatePublished - 1996
Externally publishedYes


  • reproduction techniques
  • ultrasonography

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology


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