Soy protein and serum lipids

To the Editor: In reporting the results of a meta-analysis of the effects of soy protein on serum lipid levels (Aug. 3 issue), Anderson et al.¹ commented on the position of the American Heart Association (AHA) on this issue. The conclusion of the 1993 AHA Rationale of the Diet–Heart Statement was that although there is good evidence that soy protein can lower cholesterol levels in animal models, the effects in humans, with a few exceptions, are not nearly so convincing.² Indeed, most studies included in the analysis by Anderson et al. did not show a significant reduction in levels of.