Abstract
Optical coherence tomography angiography relies on motion for contrast and requires at least two data acquisitions per pointwise scanning location. We present a method termed spectral contrast optical coherence tomography angiography using visible light that relies on the spectral signatures of blood for angiography from a single scan using endogenous contrast. We demonstrate the molecular sensitivity of this method, which enables lymphatic vessel, blood, and tissue discrimination.
| Original language | English (US) |
|---|---|
| Article number | 7 |
| Journal | Light: Science and Applications |
| Volume | 8 |
| Issue number | 1 |
| DOIs | |
| State | Published - Dec 1 2019 |
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Atomic and Molecular Physics, and Optics
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Winkelmann, J. A., Eid, A., Spicer, G., Almassalha, L. M., Nguyen, T. Q., & Backman, V. (2019). Spectral contrast optical coherence tomography angiography enables single-scan vessel imaging. Light: Science and Applications, 8(1), [7]. https://doi.org/10.1038/s41377-018-0117-7