Abstract
Optical coherence tomography angiography relies on motion for contrast and requires at least two data acquisitions per pointwise scanning location. We present a method termed spectral contrast optical coherence tomography angiography using visible light that relies on the spectral signatures of blood for angiography from a single scan using endogenous contrast. We demonstrate the molecular sensitivity of this method, which enables lymphatic vessel, blood, and tissue discrimination.
| Original language | English (US) |
|---|---|
| Article number | 7 |
| Journal | Light: Science and Applications |
| Volume | 8 |
| Issue number | 1 |
| DOIs | |
| State | Published - Dec 1 2019 |
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ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Atomic and Molecular Physics, and Optics
Cite this
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Spectral contrast optical coherence tomography angiography enables single-scan vessel imaging. / Winkelmann, James A.; Eid, Aya; Spicer, Graham; Almassalha, Luay M.; Nguyen, The Quyen; Backman, Vadim.
In: Light: Science and Applications, Vol. 8, No. 1, 7, 01.12.2019.Research output: Contribution to journal › Letter
TY - JOUR
T1 - Spectral contrast optical coherence tomography angiography enables single-scan vessel imaging
AU - Winkelmann, James A.
AU - Eid, Aya
AU - Spicer, Graham
AU - Almassalha, Luay M.
AU - Nguyen, The Quyen
AU - Backman, Vadim
PY - 2019/12/1
Y1 - 2019/12/1
N2 - Optical coherence tomography angiography relies on motion for contrast and requires at least two data acquisitions per pointwise scanning location. We present a method termed spectral contrast optical coherence tomography angiography using visible light that relies on the spectral signatures of blood for angiography from a single scan using endogenous contrast. We demonstrate the molecular sensitivity of this method, which enables lymphatic vessel, blood, and tissue discrimination.
AB - Optical coherence tomography angiography relies on motion for contrast and requires at least two data acquisitions per pointwise scanning location. We present a method termed spectral contrast optical coherence tomography angiography using visible light that relies on the spectral signatures of blood for angiography from a single scan using endogenous contrast. We demonstrate the molecular sensitivity of this method, which enables lymphatic vessel, blood, and tissue discrimination.
UR - http://www.scopus.com/inward/record.url?scp=85060350491&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85060350491&partnerID=8YFLogxK
U2 - 10.1038/s41377-018-0117-7
DO - 10.1038/s41377-018-0117-7
M3 - Letter
VL - 8
JO - Light: Science and Applications
JF - Light: Science and Applications
SN - 2095-5545
IS - 1
M1 - 7
ER -