Spectrally dependent roll-off in visible-light optical coherence tomography

Ian Rubinoff, Brian Soetikno, David A. Miller, Isabella Rischall, Amani Fawzi, Roman Kuranov, Hao F. Zhang*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Recent development of visible-light optical coherence tomography (vis-OCT) has introduced new applications for noninvasive spectroscopic imaging. However, the measured spectra may be altered by spectrally dependent roll-off (SDR). We formulated a mathematical model for SDR that accounted for nonuniform wavenumber spacing, optical aberrations, and misalignments in the spectrometer. We simulated SDR based on this model and found strong agreement with measurements from a vis-OCT system. We verified that SDR altered spectroscopic measurements of fully oxygenated blood. We corrected these alterations by normalizing each spectrally dependent A-line by the measured SDR of the spectrometer. Our investigations of SDR are critical for informing OCT spectrometer design, alignment, and spectroscopic measurements.

Original languageEnglish (US)
Pages (from-to)2680-2683
Number of pages4
JournalOptics Letters
Volume45
Issue number9
DOIs
StatePublished - May 1 2020

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

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