Spinothalamocortical inputs nonpreferentially innervate the superficial and deep cortical layers of SI

Ting Shi, Richard T. Stevens, Jeff Tessier, A. Vania Apkarian*

*Corresponding author for this work

Research output: Contribution to journalArticle

21 Scopus citations

Abstract

Using a combined anterograde and retrograde tracing technique, we examined the distribution pattern of the thalamocortical cells which projected to superficial layers of the hand region of the primary somatosensory cortex (hSI), and quantitatively analyzed the retrogradely labeled cells which putatively contacted terminals of the spinothalamic tract (STT) in the squirrel monkey and the macaque. Less than 25% of the superficial hSI projecting cells were putatively contacted by terminals of cervical enlargement spinothalamic neurons. These cells were primarily located in ventro-posterior lateral, ventroposterior inferior and centrolateral nuclei. Although the number of superficial hSI projecting cells numbered less than 20% of the total hSI projecting cells, their patterns of location and their proportion of overlap with STT terminals within each thalamic nucleus were similar. It is suggested that the spinothalamic nociceptive information input to the cortex equally accesses both superficial and deep SI.

Original languageEnglish (US)
Pages (from-to)209-213
Number of pages5
JournalNeuroscience Letters
Volume160
Issue number2
DOIs
StatePublished - Oct 1 1993

Keywords

  • Anterograde transport
  • Macaque monkey
  • Nociception
  • Retrograde transport
  • Spinothalamic terminal
  • Squirrel monkey
  • Thalamocortical cell

ASJC Scopus subject areas

  • Neuroscience(all)

Fingerprint Dive into the research topics of 'Spinothalamocortical inputs nonpreferentially innervate the superficial and deep cortical layers of SI'. Together they form a unique fingerprint.

  • Cite this