Splenic infarction, warm autoimmune hemolytic anemia and antiphospholipid antibodies in a patient with infectious mononucleosis

Elizabeth Cull, Brady Lee Stein*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

An 18-year-old woman with infectious mononucleosis developed splenic infarction and severe anemia. Evaluation of her anemia revealed a warm autoantibody and a persistently prolonged partial thromboplastin time that ultimately led to the identification of antiphospholipid antibodies. Although the warm autoantibody disappeared after 2 months, the antiphospholipid antibodies remained persistently positive. To our knowledge, this is the first case report in the literature of this specific constellation of findings, with infectious mononucleosis, warm antibody hemolytic anemia, splenic infarction and persistently positive, high-titer antiphospholipid antibodies occurring in an individual patient.

Original languageEnglish (US)
Pages (from-to)573-576
Number of pages4
JournalInternational journal of hematology
Volume95
Issue number5
DOIs
StatePublished - May 1 2012

Keywords

  • Antiphospholipid antibodies
  • Infectious mononucleosis
  • Splenic infarction

ASJC Scopus subject areas

  • Hematology

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