Spontaneous seeding of medulloblastoma: Results of cerebrospinal fluid cytology and arachnoid biopsy from the cisterna magna

Tadanori Tomita, D. G. McLone

Research output: Contribution to journalArticlepeer-review

27 Scopus citations

Abstract

Five children with cerebellar medulloblastoma underwent cytological study for neoplastic cells in the cerebrospinal fluid (CSF) from the lateral ventricle and cisterna magna and biopsy of the arachnoid of the cisterna magna before the manipulation of a medulloblastoma. In all cases, seeding of neoplastic cells was present in the CSF or arachnoid of the cisterna magna, whereas the ventricular fluid was negative for neoplastic cells. This study suggests that medulloblastoma seeds spontaneously into the subarachnoid space, thus supporting the need for postoperative whole neuraxis radiation.

Original languageEnglish (US)
Pages (from-to)265-267
Number of pages3
JournalNeurosurgery
Volume12
Issue number3
DOIs
StatePublished - Jan 1 1983

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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