Naive T lymphocytes undergo heterogeneous proliferative responses when introduced into lymphopenic hosts, referred to as "homeostatic proliferation" and "spontaneous proliferation." Spontaneous proliferation is a unique process through which the immune system generates memory phenotype cells with increasing T cell receptors repertoire complexity. Here, the mechanisms that initiate and control spontaneous proliferation are discussed.
|Original language||English (US)|
|Journal||Frontiers in immunology|
|State||Published - Mar 19 2018|
- T cells
ASJC Scopus subject areas
- Immunology and Allergy