SQUID-detected microtesla MRI in the presence of metal

Michael Mößle; Song I. Han; Whittier R. Myers; Seung Kyun Lee; Nathan Kelso; Michael Hatridge; Alexander Pines; John Clarke

doi:10.1016/j.jmr.2005.11.005

SQUID-detected microtesla MRI in the presence of metal

Michael Mößle^*, Song I. Han, Whittier R. Myers, Seung Kyun Lee, Nathan Kelso, Michael Hatridge, Alexander Pines, John Clarke

^*Corresponding author for this work

Chemistry

Research output: Contribution to journal › Article › peer-review

108 Scopus citations

Abstract

In magnetic resonance imaging performed at fields of 1 T and above, the presence of a metal insert can distort the image because of susceptibility differences within the sample and modification of the radiofrequency fields by screening currents. Furthermore, it is not feasible to perform nuclear magnetic resonance (NMR) spectroscopy or acquire a magnetic resonance image if the sample is enclosed in a metal container. Both problems can be overcome by substantially lowering the NMR frequency. Using a microtesla imaging system operating at 2.8 kHz, with a superconducting quantum interference device as the signal detector, we have obtained distortion-free images of a phantom containing a titanium bar and three-dimensional images of an object enclosed in an aluminum can; in both cases high-field images are inaccessible.

Original language	English (US)
Pages (from-to)	146-151
Number of pages	6
Journal	Journal of Magnetic Resonance
Volume	179
Issue number	1
DOIs	https://doi.org/10.1016/j.jmr.2005.11.005
State	Published - Mar 2006

Keywords

Low field
Magnetic resonance imaging
RF screening
SQUID detection
Susceptibility artifacts

ASJC Scopus subject areas

Biophysics
Biochemistry
Nuclear and High Energy Physics
Condensed Matter Physics

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10.1016/j.jmr.2005.11.005

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title = "SQUID-detected microtesla MRI in the presence of metal",

abstract = "In magnetic resonance imaging performed at fields of 1 T and above, the presence of a metal insert can distort the image because of susceptibility differences within the sample and modification of the radiofrequency fields by screening currents. Furthermore, it is not feasible to perform nuclear magnetic resonance (NMR) spectroscopy or acquire a magnetic resonance image if the sample is enclosed in a metal container. Both problems can be overcome by substantially lowering the NMR frequency. Using a microtesla imaging system operating at 2.8 kHz, with a superconducting quantum interference device as the signal detector, we have obtained distortion-free images of a phantom containing a titanium bar and three-dimensional images of an object enclosed in an aluminum can; in both cases high-field images are inaccessible.",

keywords = "Low field, Magnetic resonance imaging, RF screening, SQUID detection, Susceptibility artifacts",

author = "Michael M{\"o}{\ss}le and Han, {Song I.} and Myers, {Whittier R.} and Lee, {Seung Kyun} and Nathan Kelso and Michael Hatridge and Alexander Pines and John Clarke",

note = "Funding Information: The authors thank Christian Hilty and Josef Granwehr for their help with the high-field images. This work was supported by the Director, Office of Science, Office of Basic Energy Sciences, Division of Materials Sciences and Engineering of the US Department of Energy under Contract No. DE-AC03-76SF00098. M. M{\"o}{\ss}le acknowledges the “Deutsche Forschungsgemeinschaft” for a postdoctoral fellowship.",

year = "2006",

month = mar,

doi = "10.1016/j.jmr.2005.11.005",

language = "English (US)",

volume = "179",

pages = "146--151",

journal = "Journal of Magnetic Resonance",

issn = "1090-7807",

publisher = "Academic Press Inc.",

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T1 - SQUID-detected microtesla MRI in the presence of metal

AU - Mößle, Michael

AU - Han, Song I.

AU - Myers, Whittier R.

AU - Lee, Seung Kyun

AU - Kelso, Nathan

AU - Hatridge, Michael

AU - Pines, Alexander

AU - Clarke, John

N1 - Funding Information: The authors thank Christian Hilty and Josef Granwehr for their help with the high-field images. This work was supported by the Director, Office of Science, Office of Basic Energy Sciences, Division of Materials Sciences and Engineering of the US Department of Energy under Contract No. DE-AC03-76SF00098. M. Mößle acknowledges the “Deutsche Forschungsgemeinschaft” for a postdoctoral fellowship.

PY - 2006/3

Y1 - 2006/3

N2 - In magnetic resonance imaging performed at fields of 1 T and above, the presence of a metal insert can distort the image because of susceptibility differences within the sample and modification of the radiofrequency fields by screening currents. Furthermore, it is not feasible to perform nuclear magnetic resonance (NMR) spectroscopy or acquire a magnetic resonance image if the sample is enclosed in a metal container. Both problems can be overcome by substantially lowering the NMR frequency. Using a microtesla imaging system operating at 2.8 kHz, with a superconducting quantum interference device as the signal detector, we have obtained distortion-free images of a phantom containing a titanium bar and three-dimensional images of an object enclosed in an aluminum can; in both cases high-field images are inaccessible.

AB - In magnetic resonance imaging performed at fields of 1 T and above, the presence of a metal insert can distort the image because of susceptibility differences within the sample and modification of the radiofrequency fields by screening currents. Furthermore, it is not feasible to perform nuclear magnetic resonance (NMR) spectroscopy or acquire a magnetic resonance image if the sample is enclosed in a metal container. Both problems can be overcome by substantially lowering the NMR frequency. Using a microtesla imaging system operating at 2.8 kHz, with a superconducting quantum interference device as the signal detector, we have obtained distortion-free images of a phantom containing a titanium bar and three-dimensional images of an object enclosed in an aluminum can; in both cases high-field images are inaccessible.

KW - Low field

KW - Magnetic resonance imaging

KW - RF screening

KW - SQUID detection

KW - Susceptibility artifacts

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JO - Journal of Magnetic Resonance

JF - Journal of Magnetic Resonance

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ER -

SQUID-detected microtesla MRI in the presence of metal

Abstract

Keywords

ASJC Scopus subject areas

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