Stain intensity of human nucleolus organizer region reflects incorporation of uridine into mature ribosomal RNA

C. C. Morton, J. A. Brown, W. M. Holmes, W. E. Nance, B. Wolf*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

49 Scopus citations

Abstract

The stain intensity of the nucleotus organizer regions (NORs) of acrocentric chromosomes was correlated positively with incorporation of [3H]uridine into 18S rRNA and 28S rRNA from cultured diploid human skin fibroblasts. An analysis of these data from twins by a path model indicated that no other common genetic or environmental parameters were required to explain the relationship between NOR scores and uptake of [3H]uridine into mature rRNA species.

Original languageEnglish (US)
Pages (from-to)405-413
Number of pages9
JournalExperimental Cell Research
Volume145
Issue number2
DOIs
StatePublished - May 1983

ASJC Scopus subject areas

  • Cell Biology

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