TY - JOUR
T1 - Standardization of Epidemiological Surveillance of Group A Streptococcal Pharyngitis
AU - Strep A Vaccine Global Consortium (SAVAC) Burden of Disease Working Group
AU - Miller, Kate M.
AU - Tanz, Robert R.
AU - Shulman, Stanford T.
AU - Carapetis, Jonathan R.
AU - Cherian, Thomas
AU - Lamagni, Theresa
AU - Bowen, Asha C.
AU - Pickering, Janessa
AU - Fulurija, Alma
AU - Moore, Hannah C.
AU - Cannon, Jeffrey W.
AU - Barnett, Timothy C.
AU - Van Beneden, Chris A.
AU - Carapetis, Jonathan
AU - Van Beneden, Chris
AU - Kaslow, David C.
AU - Cherian, Thomas
AU - Lamagni, Theresa
AU - Engel, Mark
AU - Cannon, Jeffrey
AU - Moore, Hannah C.
AU - Bowen, Asha
AU - Seale, Anna
AU - Kang, Gagandeep
AU - Watkins, David
AU - Kariuki, Sam
N1 - Publisher Copyright:
© 2022 The Author(s). Published by Oxford University Press on behalf of Infectious Diseases Society of America.
PY - 2022/9/1
Y1 - 2022/9/1
N2 - Pharyngitis, more commonly known as sore throat, is caused by viral and/or bacterial infections. Group A Streptococcus (Strep A) is the most common bacterial cause of pharyngitis. Strep A pharyngitis is an acute, self-limiting disease but if undertreated can lead to suppurative complications, nonsuppurative poststreptococcal immune-mediated diseases, and toxigenic presentations. We present a standardized surveillance protocol, including case definitions for pharyngitis and Strep A pharyngitis, as well as case classifications that can be used to differentiate between suspected, probable, and confirmed cases. We discuss the current tests used to detect Strep A among persons with pharyngitis, including throat culture and point-of-care tests. The type of surveillance methodology depends on the resources available and the objectives of surveillance. Active surveillance and laboratory confirmation is the preferred method for case detection. Participant eligibility, the surveillance population and additional considerations for surveillance of pharyngitis are addressed, including baseline sampling, community engagement, frequency of screening and season. Finally, we discuss the core elements of case report forms for pharyngitis and provide guidance for the recording of severity and pain associated with the course of an episode.
AB - Pharyngitis, more commonly known as sore throat, is caused by viral and/or bacterial infections. Group A Streptococcus (Strep A) is the most common bacterial cause of pharyngitis. Strep A pharyngitis is an acute, self-limiting disease but if undertreated can lead to suppurative complications, nonsuppurative poststreptococcal immune-mediated diseases, and toxigenic presentations. We present a standardized surveillance protocol, including case definitions for pharyngitis and Strep A pharyngitis, as well as case classifications that can be used to differentiate between suspected, probable, and confirmed cases. We discuss the current tests used to detect Strep A among persons with pharyngitis, including throat culture and point-of-care tests. The type of surveillance methodology depends on the resources available and the objectives of surveillance. Active surveillance and laboratory confirmation is the preferred method for case detection. Participant eligibility, the surveillance population and additional considerations for surveillance of pharyngitis are addressed, including baseline sampling, community engagement, frequency of screening and season. Finally, we discuss the core elements of case report forms for pharyngitis and provide guidance for the recording of severity and pain associated with the course of an episode.
KW - Streptococcus pyogenes
KW - epidemiology
KW - infectious disease
KW - pharyngitis
KW - surveillance
UR - http://www.scopus.com/inward/record.url?scp=85159578038&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85159578038&partnerID=8YFLogxK
U2 - 10.1093/ofid/ofac251
DO - 10.1093/ofid/ofac251
M3 - Article
C2 - 36128410
AN - SCOPUS:85159578038
SN - 2328-8957
VL - 9
SP - S5-S14
JO - Open Forum Infectious Diseases
JF - Open Forum Infectious Diseases
ER -