Standardized Use of the Stanford Integrated Psychosocial Assessment for Transplantation in LVAD Patients

MATTHEW Cagliostro, ANDREW BROMLEY, PETER TING, J. O.H.N. DONEHEY, B. A.R.T. FERKET, K. I.R.A. PARKS, ELYSE PALUMBO, DONNA MANCINI, ANELECHI ANYANWU, Amit Pawale, S. E.A.N. PINNEY, N. O.A.H. MOSS, ANURADHA LALA*

*Corresponding author for this work

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Background: Increased psychosocial risk portends poor outcomes following heart transplantation. The Stanford Integrated Psychosocial Assessment for Transplantation (SIPAT) is a validated, psychosocial risk assessment tool that helps stratify candidates for transplantation. We assessed the impact of psychosocial factors as measured by the SIPAT on clinical outcomes following left ventricular assist device (LVAD) implantation at our institution. Methods and Results: A total of 115 individuals (mean age: 57 years, 75.6% men) who underwent LVAD implantation, for either bridge-to-transplant (63%) or destination therapy, from 2014 to 2016 were included for analysis. Correlations between SIPAT scores, baseline characteristics, and post-LVAD outcomes were assessed through a retrospective correlational design. At 1 year post-LVAD, the higher risk SIPAT group had more emergency department visits, urgent clinic visits, and readmissions in univariate analysis (rate ratio 1.7 [95% confidence interval (CI) 1.0–2.7, P = .035]). After multivariate analysis, this association retained near-statistical significance (rate ratio 1.6 [95% CI 1.0–2.8, P = .051]). There was also a trend toward more device-associated infections (rate ratio 2.1 [95% CI 0.96–4.4, P = .064]). There was no difference in incidence of other adverse events or 1-year mortality between the 2 groups. Conclusions: Higher psychosocial risk per SIPAT in patients undergoing LVAD implantation is associated with more emergency room visits, urgent visits and readmissions over 1 year, but not LVAD-related complications or mortality. Use of the SIPAT tool may help identify patients at higher risk for hospitalization and/or urgent care beyond traditional factors, but should not preclude LVAD implantation.

Original languageEnglish (US)
Pages (from-to)735-743
Number of pages9
JournalJournal of Cardiac Failure
Volume25
Issue number9
DOIs
Publication statusPublished - Sep 2019

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Keywords

  • Heart failure
  • LVAD
  • Stanford Integrated Psychosocial Assessment for Transplantation
  • device-associated infections
  • driveline-associated infection
  • orthotopic heart transplantation

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Cagliostro, MATTHEW., BROMLEY, ANDREW., TING, PETER., DONEHEY, J. O. H. N., FERKET, B. A. R. T., PARKS, K. I. R. A., ... LALA, ANURADHA. (2019). Standardized Use of the Stanford Integrated Psychosocial Assessment for Transplantation in LVAD Patients. Journal of Cardiac Failure, 25(9), 735-743. https://doi.org/10.1016/j.cardfail.2019.06.006