Standards of care and novel approaches in the management of glioblastoma multiforme

Andreas F. Hottinger, Roger Stupp, Krisztian Homicsko

Research output: Contribution to journalReview articlepeer-review

77 Scopus citations

Abstract

Glioblastoma multiforme (GBM) is the most common malignant primary brain tumor in adults. Standard therapeutic approaches provide modest improvement in the progression-free and overall survival, necessitating the investigation of novel therapies. We review the standard treatment options for GBM and evaluate the results obtained in clinical trials for promising novel approaches, including the inhibition of angiogenesis, targeted approaches against molecular pathways, immunotherapies, and local treatment with low voltage electric fields.

Original languageEnglish (US)
Pages (from-to)32-39
Number of pages8
JournalChinese Journal of Cancer
Volume33
Issue number1
DOIs
StatePublished - 2014

Keywords

  • Angiogenesis
  • Electric fields
  • Glioblastoma multiforme
  • Immunotherapy
  • Targeted agents
  • Treatment

ASJC Scopus subject areas

  • Oncology

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