Abstract
In attempting to manipulate epileptiform bursting in the rat brain, one approach is to apply nonlinear chaos control techniques to alter this spontaneous electrical activity. A key element to implementing this technique is identification of unstable periodic orbits (UPOs), especially period-1 orbits and the location of fixed points within state space around which the bursting can be manipulated. However, experimental factors such as physiological noise and system non-stationarity have the potential to make the accuracy of fixed point location prone to inaccuracy. We developed a technique known as state point forcing in which we statistically compare the temporal evolution of a system state brought close to the postulated fixed point relative to other locations chosen within state space. This technique verified that our calculations of UPO location during spontaneous bursting in rat hippocampus were functionally accurate.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1921-1924 |
| Number of pages | 4 |
| Journal | Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings |
| Volume | 2 |
| State | Published - 2003 |
| Event | A New Beginning for Human Health: Proceddings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Cancun, Mexico Duration: Sep 17 2003 → Sep 21 2003 |
Keywords
- Chaos control
- Epilepsy
- Hippocampus
- Nonlinear
ASJC Scopus subject areas
- Signal Processing
- Biomedical Engineering
- Computer Vision and Pattern Recognition
- Health Informatics