@article{43516ebaf23b42b3ab6eefc81c74493d,
title = "Statin-associated muscle symptoms in the VITamin D and OmegA-3 TriaL (VITAL)",
abstract = "Statins are highly effective medications that reduce risk of atherosclerotic cardiovascular disease, but are very commonly discontinued by patients because of muscle symptoms. The risk factors for statin-associated muscle symptoms (SAMS) are not well understood, so in this study we examined the predictors of SAMS in a well-studied cohort of patients in the VITAL trial. We found that female sex and younger age (50-64 years) were significant, independent predictors of higher rates of SAMS.",
author = "Gonzalez, {Pedro Engel} and Hlatky, {Mark A.} and Manson, {Jo Ann E.} and Buring, {Julie E.} and Lee, {I. Min} and Cook, {Nancy R.} and Vadim Bubes and Stone, {Neil J.}",
note = "Funding Information: This study was supported by the Hyperlipidemia Research Fund at Northwestern University. The VITAL trial was supported by grants (R01 AT011729, U01 CA138962, and R01 CA138962) from the National Institutes of Health. The authors are solely responsible for the design and conduct of this study, all study analyses, the drafting and editing of the paper, and its final contents. The authors have no relationships with industry to declare. Publisher Copyright: {\textcopyright} 2022 Elsevier Inc.",
year = "2022",
month = oct,
doi = "10.1016/j.ahj.2022.06.001",
language = "English (US)",
volume = "252",
pages = "39--41",
journal = "American Heart Journal",
issn = "0002-8703",
publisher = "Mosby Inc.",
}
