Abstract
A statistical approach to the selection of solvent systems for two-dimensional thin-layer chromatography Is presented. Two functions are used as separation criteria for evaluating 28 two-dimensional solvent systems for the separation of each of 100 subsets of either six or ten steroids, randomly selected from a set of 15 steroids. This approach allows a probability to be assigned to each solvent system of its being highest ranked for separating any given subset of steroids. This probability varies from 0% to 49% for the solvent systems considered; It is influenced by size of the subset considered and, to a lesser extent, by the selection of separation criterion used.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 2424-2428 |
| Number of pages | 5 |
| Journal | Analytical Chemistry |
| Volume | 59 |
| Issue number | 19 |
| DOIs | |
| State | Published - 1987 |
ASJC Scopus subject areas
- Analytical Chemistry