Stimulation of dorsal midbrain during septal and hypothalamic self-stimulation

Aryeh Routtenberg; James Olds

doi:10.1037/h0023664

Stimulation of dorsal midbrain during septal and hypothalamic self-stimulation

Aryeh Routtenberg^*, James Olds

^*Corresponding author for this work

Psychology

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

3 experiments were performed to study the effects of aversive dorsal midbrain (DM) stimulation on posterior hypothalamic or septal self-stimulation. In Exp. I, both posterior hypothalamic and septal self-stimulation rates were reduced by crystalline carbachol stimulation of DM, but posterior hypothalamic self-stimulation was reduced significantly more. In Exp. II, injection of liquid carbachol into DM suggested that .75-2.25 micrograms of chemical are necessary for suppression of hypothalamic self-stimulation. In Exp. III, which repeated Exp. I using electrical stimulation of DM, DM electrical stimulation reduced self-stimulation behavior, and hypothalamic self-stimulation was reduced significantly more. Septal and hypothalamic self-stimulation are compared in terms of their relation to DM. (PsycINFO Database Record (c) 2006 APA, all rights reserved).

Original language	English (US)
Pages (from-to)	250-255
Number of pages	6
Journal	Journal of Comparative and Physiological Psychology
Volume	62
Issue number	2
DOIs	https://doi.org/10.1037/h0023664
State	Published - Oct 1 1966

Keywords

BRAIN STIMULATION
DORSAL MIDBRAIN STIMULATION
DORSAL MIDBRAIN STIMULATION, RAT
HYPOTHALAMIC SELF STIMULATION &
HYPOTHALAMIC, &
RAT, SEPTAL &
SELF-STIMULATION, SEPTAL &

ASJC Scopus subject areas

Medicine(all)

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10.1037/h0023664

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title = "Stimulation of dorsal midbrain during septal and hypothalamic self-stimulation",

abstract = "3 experiments were performed to study the effects of aversive dorsal midbrain (DM) stimulation on posterior hypothalamic or septal self-stimulation. In Exp. I, both posterior hypothalamic and septal self-stimulation rates were reduced by crystalline carbachol stimulation of DM, but posterior hypothalamic self-stimulation was reduced significantly more. In Exp. II, injection of liquid carbachol into DM suggested that .75-2.25 micrograms of chemical are necessary for suppression of hypothalamic self-stimulation. In Exp. III, which repeated Exp. I using electrical stimulation of DM, DM electrical stimulation reduced self-stimulation behavior, and hypothalamic self-stimulation was reduced significantly more. Septal and hypothalamic self-stimulation are compared in terms of their relation to DM. (PsycINFO Database Record (c) 2006 APA, all rights reserved).",

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author = "Aryeh Routtenberg and James Olds",

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AU - Olds, James

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N2 - 3 experiments were performed to study the effects of aversive dorsal midbrain (DM) stimulation on posterior hypothalamic or septal self-stimulation. In Exp. I, both posterior hypothalamic and septal self-stimulation rates were reduced by crystalline carbachol stimulation of DM, but posterior hypothalamic self-stimulation was reduced significantly more. In Exp. II, injection of liquid carbachol into DM suggested that .75-2.25 micrograms of chemical are necessary for suppression of hypothalamic self-stimulation. In Exp. III, which repeated Exp. I using electrical stimulation of DM, DM electrical stimulation reduced self-stimulation behavior, and hypothalamic self-stimulation was reduced significantly more. Septal and hypothalamic self-stimulation are compared in terms of their relation to DM. (PsycINFO Database Record (c) 2006 APA, all rights reserved).

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Stimulation of dorsal midbrain during septal and hypothalamic self-stimulation

Abstract

Keywords

ASJC Scopus subject areas

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