Stochastic feedback and the regulation of biological rhythms

P. Ch Ivanov*, L. A. Nunes Amaral, A. L. Goldberger, H. E. Stanley

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

191 Scopus citations


We propose a general approach to the question of how biological rhythms spontaneously self-regulate, based on the concept of "stochastic feedback". We illustrate this approach by considering at a coarse-grained level the neuroautonomic regulation of the heart rate. The model generates complex dynamics and successfully accounts for key characteristics of cardiac variability, including the 1/f power spectrum, the functional form and scaling of the distribution of variations, and correlations in the Fourier phases indicating nonlinear dynamics.

Original languageEnglish (US)
Pages (from-to)363-368
Number of pages6
JournalEurophysics Letters
Issue number4
StatePublished - Aug 15 1998

ASJC Scopus subject areas

  • Physics and Astronomy(all)


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