Strategies for Incorporating Catalytically Active Polyoxometalates in Metal-Organic Frameworks for Organic Transformations

Polyoxometalates (POMs) can benefit from immobilization on solid supports to overcome their difficulty in processability and stability. Among the reported solid supports, metal-organic frameworks (MOFs) offer a crystalline, versatile platform for depositing highly active POMs. The combination of these structures can at times benefit from the combined reactivity of both the POM and MOF, sometimes synergistically, to improve catalysis while balancing desirable properties like porosity, substrate diffusion, or stability. In this Review, we survey the strategies for immobilizing POMs within MOF structures, with an emphasis on how physical and catalytic properties of the parent materials are affected in the composite when employed in organic transformations.