Strengthening the reporting of observational studies in epidemiology using mendelian randomisation (STROBE-MR): Explanation and elaboration

Veronika W. Skrivankova, Rebecca C. Richmond, Benjamin A.R. Woolf, Neil M. Davies, Sonja A. Swanson, Tyler J. Vanderweele, Nicholas J. Timpson, Julian P.T. Higgins, Niki Dimou, Claudia Langenberg, Elizabeth W. Loder, Robert M. Golub, Matthias Egger, George Davey Smith, J. Brent Richards*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

Mendelian randomisation (MR) studies allow a better understanding of the causal effects of modifiable exposures on health outcomes, but the published evidence is often hampered by inadequate reporting. Reporting guidelines help authors effectively communicate all critical information about what was done and what was found. STROBE-MR (strengthening the reporting of observational studies in epidemiology using mendelian randomisation) assists authors in reporting their MR research clearly and transparently. Adopting STROBE-MR should help readers, reviewers, and journal editors evaluate the quality of published MR studies. This article explains the 20 items of the STROBE-MR checklist, along with their meaning and rationale, using terms defined in a glossary. Examples of transparent reporting are used for each item to illustrate best practices.

Original languageEnglish (US)
Article numbern2233
JournalThe BMJ
Volume375
DOIs
StatePublished - Oct 26 2021

ASJC Scopus subject areas

  • Medicine(all)

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