Stress-reactivity of a Drosophila melanogaster strain with impaired juvenile hormone action

N. E. Gruntenko*, T. M. Khlebodarova, I. A. Vasenkova, M. Jh Sukhanova, T. G. Wilson, I. Yu Rauschenbach

*Corresponding author for this work

Research output: Contribution to journalArticle

20 Scopus citations

Abstract

Met27 is a null allele of the Methoprene-tolerant gene of D. melanogaster that shows resistance to the toxic effects of both juvenile hormone (JH) and a JH analog, methoprene. The mechanism of resistance appears to be altered JH reception. We measured fertility, JH-hydrolyzing activity, and dopamine (DA) levels in Met27 and Met+ flies under normal (25°C) and heat-stress (38°C) conditions. We show that under normal conditions Met27 females have JH-hydrolyzing activity and fertility lower than Met+, but DA content did not differ between the two strains. AT 38°C Met27 flies show no impairment in JH-hydrolyzing activity in response to stress, but they do show lower DA levels and impaired reproduction. The results with Met27 are consistent with the previous hypothesis that the alteration in fertility that follows heat stress in D. melanogaster could result from alteration in the JH endocrine system. (C) 2000 Elsevier Science Ltd.

Original languageEnglish (US)
Pages (from-to)451-456
Number of pages6
JournalJournal of Insect Physiology
Volume46
Issue number4
DOIs
StatePublished - Apr 1 2000
Externally publishedYes

Keywords

  • Dopamine melanogaster
  • Heat stress
  • Juvenile hormone
  • Reproduction

ASJC Scopus subject areas

  • Physiology
  • Insect Science

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    Gruntenko, N. E., Khlebodarova, T. M., Vasenkova, I. A., Sukhanova, M. J., Wilson, T. G., & Rauschenbach, I. Y. (2000). Stress-reactivity of a Drosophila melanogaster strain with impaired juvenile hormone action. Journal of Insect Physiology, 46(4), 451-456. https://doi.org/10.1016/S0022-1910(99)00131-6