TY - JOUR
T1 - Stretchable, wireless sensors and functional substrates for epidermal characterization of sweat
AU - Huang, Xian
AU - Liu, Yuhao
AU - Chen, Kaile
AU - Shin, Woo Jung
AU - Lu, Ching Jui
AU - Kong, Gil Woo
AU - Patnaik, Dwipayan
AU - Lee, Sang Heon
AU - Cortes, Jonathan Fajardo
AU - Rogers, John A.
PY - 2014/8/13
Y1 - 2014/8/13
N2 - This paper introduces materials and architectures for ultrathin, stretchable wireless sensors that mount on functional elastomeric substrates for epidermal analysis of biofluids. Measurement of the volume and chemical properties of sweat via dielectric detection and colorimetry demonstrates some capabilities. Here, inductively coupled sensors consisting of LC resonators with capacitive electrodes show systematic responses to sweat collected in microporous substrates. Interrogation occurs through external coils placed in physical proximity to the devices. The substrates allow spontaneous sweat collection through capillary forces, without the need for complex microfluidic handling systems. Furthermore, colorimetric measurement modes are possible in the same system by introducing indicator compounds into the depths of the substrates, for sensing specific components (OH-, H+, Cu+, and Fe2+) in the sweat. The complete devices offer Young's moduli that are similar to skin, thus allowing highly effective and reliable skin integration without external fixtures. Experimental results demonstrate volumetric measurement of sweat with an accuracy of 0.06 μL/mm2 with good stability and low drift. Colorimetric responses to pH and concentrations of various ions provide capabilities relevant to analysis of sweat. Similar materials and device designs can be used in monitoring other body fluids. This paper introduces materials and architectures for ultrathin, stretchable wireless sensors that mount on functional elastomeric substrates for epidermal analysis of biofluids. Experimental results demonstrate volumetric measurement of sweat with high accuracy as well as good stability and low drift. Colorimetric responses to pH and concentrations of various ions demonstrate capabilities relevant to chemical analysis of sweat.
AB - This paper introduces materials and architectures for ultrathin, stretchable wireless sensors that mount on functional elastomeric substrates for epidermal analysis of biofluids. Measurement of the volume and chemical properties of sweat via dielectric detection and colorimetry demonstrates some capabilities. Here, inductively coupled sensors consisting of LC resonators with capacitive electrodes show systematic responses to sweat collected in microporous substrates. Interrogation occurs through external coils placed in physical proximity to the devices. The substrates allow spontaneous sweat collection through capillary forces, without the need for complex microfluidic handling systems. Furthermore, colorimetric measurement modes are possible in the same system by introducing indicator compounds into the depths of the substrates, for sensing specific components (OH-, H+, Cu+, and Fe2+) in the sweat. The complete devices offer Young's moduli that are similar to skin, thus allowing highly effective and reliable skin integration without external fixtures. Experimental results demonstrate volumetric measurement of sweat with an accuracy of 0.06 μL/mm2 with good stability and low drift. Colorimetric responses to pH and concentrations of various ions provide capabilities relevant to analysis of sweat. Similar materials and device designs can be used in monitoring other body fluids. This paper introduces materials and architectures for ultrathin, stretchable wireless sensors that mount on functional elastomeric substrates for epidermal analysis of biofluids. Experimental results demonstrate volumetric measurement of sweat with high accuracy as well as good stability and low drift. Colorimetric responses to pH and concentrations of various ions demonstrate capabilities relevant to chemical analysis of sweat.
KW - epidermal electronics
KW - flexible electronics
KW - stretchable electronics
KW - sweat sensor
KW - wireless sensor
UR - http://www.scopus.com/inward/record.url?scp=84905648758&partnerID=8YFLogxK
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U2 - 10.1002/smll.201400483
DO - 10.1002/smll.201400483
M3 - Article
C2 - 24706477
AN - SCOPUS:84905648758
SN - 1613-6810
VL - 10
SP - 3083
EP - 3090
JO - Small
JF - Small
IS - 15
ER -