Structural and optical characterization of single nanoparticles and single molecule SERS

Samuel L. Kleinman, Julia M. Bingham, Anne Isabelle Henry, Kristin L. Wustholz, Richard P Van Duyne

Research output: Chapter in Book/Report/Conference proceedingConference contribution

7 Scopus citations


Although plasmonic nanoparticles are widely utilized in spectroscopy and sensing applications, a quantitative structure-function relationship is lacking. In this proceeding, we discuss measurements of single noble metal nanoparticles using localized surface plasmon resonance (LSPR) spectroscopy, surface-enhanced Raman spectroscopy (SERS), and transmission electron microscopy (TEM) to elucidate structure-function relationships. A recently developed LSPR imaging spectroscopy instrument with an extremely fast camera enables measurement of diffusion constants for individual silver nanoprisms dispersed in water-paving the way for plasmonic particles as dynamic labels in biological systems. Correlated studies involving two or all three of these techniques relate optical properties of the same nanoparticle to its structure. Lastly, singlemolecule surface-enhanced Raman spectroscopy of Rhodamine 6G is explored on lithographically fabricated plasmonic structures.

Original languageEnglish (US)
Title of host publicationPlasmonics
Subtitle of host publicationMetallic Nanostructures and Their Optical Properties VIII
StatePublished - Dec 1 2010
EventPlasmonics: Metallic Nanostructures and Their Optical Properties VIII - San Diego, CA, United States
Duration: Aug 1 2010Aug 5 2010


OtherPlasmonics: Metallic Nanostructures and Their Optical Properties VIII
CountryUnited States
CitySan Diego, CA


  • Localized surface plasmon resonance
  • Nanoprisms
  • Rhodamine
  • SERS nanotags
  • Single-nanoparticle spectroscopy
  • Surface-enhanced Raman spectroscopy
  • Transmission electron microscopy
  • Wide-field imaging

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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