Structural details of rat extraocular muscles and three-dimensional reconstruction of the rat inferior rectus muscle and muscle-pulley interface

Edward Felder, Sasha Bogdanovich, Neal A. Rubinstein, Tejvir S. Khurana*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

Light microscopy, electron microscopy and morphometry revealed structural details and allowed generation of a three-dimensional reconstruction of the pulley and muscle-pulley interface of extraocular muscle. The inferior rectus orbital layer was bifurcate in shape and extended anterior to the pulley. The putative pulley structure itself was asymmetric; loosely attached at the orbital aspect it adhered tightly to the global aspect of muscle. Orbital multiply innervated fiber proportion increased anterior to the pulley insertion site. Additionally longitudinal variation in juxtaposition of orbital and global layers was noted. These newly described structural details provide novel mechanistic insight for extraocular muscle function in rats.

Original languageEnglish (US)
Pages (from-to)1945-1955
Number of pages11
JournalVision Research
Volume45
Issue number15
DOIs
StatePublished - Jul 2005

Keywords

  • Eye movement
  • Eye muscle
  • Global layer
  • Multiply innervated fibers
  • Orbital layer
  • Pulley
  • Single innervated fibers
  • Three-dimensional reconstruction

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems

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