Abrupt transitions between states of different extensions driven by stretching and twisting were shown by experiments on single DNA molecules. The analysis showed that a statistical-mechanical model was used to globally fit experimental force-extension data over a wide-range of DNA molecule twisting. The mean twist, free energies, and extensions of the five DNA states were obtained experimentally and global force-torque and force-linking number phase diagrams for DNA were predicted.
|Number of pages
|Physical Review E - Statistical, Nonlinear, and Soft Matter Physics
|Published - May 2001
ASJC Scopus subject areas
- Condensed Matter Physics
- Statistical and Nonlinear Physics
- Statistics and Probability