Keyphrases
Structure-based Design
100%
Drug Resistance
100%
HIV-1 Protease
100%
HIV Protease Inhibitors
100%
Active Sites
66%
Design Strategy
33%
Novel Inhibitors
33%
X-ray Crystal Structure
33%
Isostere
33%
Meso
33%
Optically Active
33%
Clinical Strains
33%
Lewis Acid Catalysis
33%
Furan
33%
Hydrogen Bonding Interaction
33%
Urethane
33%
Inhibitory Potency
33%
Acetylcholinesterase
33%
Diacetate
33%
Protein-ligand
33%
Strong Hydrogen Bond
33%
Sulfonamides
33%
Enzyme Inhibitory Activity
33%
Antiviral Potency
33%
P2 Ligand
33%
Radical Cyclization
33%
Asymmetrization
33%
Pharmacology, Toxicology and Pharmaceutical Science
Proteinase Inhibitor
100%
Human Immunodeficiency Virus Proteinase
100%
Drug Resistance
100%
HIV
25%
Sulfonamide
25%
Ethyl Carbamate
25%
Antivirus Agent
25%
Lewis Acid
25%
Acetoacetic Acid
25%
Protein Ligand
25%
Human Immunodeficiency Virus Proteinase Inhibitor
25%
Furan
25%
Acetylcholinesterase
25%
Biochemistry, Genetics and Molecular Biology
Protease Inhibitor
100%
Drug Resistance
100%
HIV-1 Protease
100%
Active Site
50%
Crystal Structure
25%
X Ray
25%
HIV Protease Inhibitor
25%
Enzyme
25%
Human Immunodeficiency Virus
25%
Protein Ligand
25%
Acetylcholinesterase
25%
Sulfonamide
25%